Results 121 to 130 of about 18,661,987 (346)

Amino acid interactions of spiropyran [PDF]

, 2008
A solution phase study was carried out to explore the interactions between the spiropyran molecule in its merocyanine zwitterionic merocyanine 'open' form and amino acids.
Dalton, Gene
core   +2 more sources

Signatures of host specialization and a recent transposable element burst in the dynamic one-speed genome of the fungal barley powdery mildew pathogen

BMC Genomics, 2018
Background Powdery mildews are biotrophic pathogenic fungi infecting a number of economically important plants. The grass powdery mildew, Blumeria graminis, has become a model organism to study host specialization of obligate biotrophic fungal pathogens.
Lamprinos Frantzeskakis, Barbara Kracher, Stefan Kusch, Makoto Yoshikawa-Maekawa, Saskia Bauer, Carsten Pedersen, Pietro D. Spanu, Takaki Maekawa, Paul Schulze-Lefert, Ralph Panstruga   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Revealing the molecular signatures of host-pathogen interactions. [PDF]

, 2011
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
Martin L Hibberd, Khor, C.-C., Hibberd, Martin L, Chiea-Chuen Khor, Hibberd, M.L., Khor, Chiea-Chuen   +5 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Noncovalent interactions between hydroxylated polycyclic aromatic hydrocarbon and DNA: Molecular docking and QSAR study

, 2011
Polycyclic aromatic hydrocarbons (PAHs) can be hydroxylated by CYP450-oxidases (1A1 and 1B1 mainly) and may cause DNA damage and cancer. However, the mechanism of such interactions has not been fully understood.
Fei Li, Jianmin Zhao, You, Liping, Xuehua Li, Xiaoli Liu, Liu, Xiaoli, Liping You, Wu, Huifeng, Huifeng Wu, Li, Xuehua, Linbao Zhang, Li, Fei, Zhang, Linbao, Zhao, Jianmin   +13 more
core   +1 more source

Antibacterial Activity and Proposed Mode of Action of Extracts from Selected Zimbabwean Medicinal Plants against Acinetobacter baumannii

Advances in Pharmacological and Pharmaceutical Sciences
Acinetobacter baumannii was identified by the WHO as a priority pathogen in which the research and development of new antibiotics is urgently needed. Plant phytochemicals have potential as sources of new antimicrobials.
Auxillia Machingauta, Stanley Mukanganyama   +1 more
doaj   +1 more source

Revisiting the Soybean GmNAC Superfamily

Frontiers in Plant Science, 2018
The NAC (NAM, ATAF, and CUC) genes encode transcription factors involved with the control of plant morph-physiology and stress responses. The release of the last soybean (Glycine max) genome assembly (Wm82.a2.v1) raised the possibility that new NAC genes
Bruno P. Melo, Bruno P. Melo, Otto T. Fraga, Otto T. Fraga, José Cleydson F. Silva, Dalton O. Ferreira, Otávio J. B. Brustolini, Paola A. Carpinetti, Joao Paulo B. Machado, Pedro A. B. Reis, Pedro A. B. Reis, Elizabeth P. B. Fontes, Elizabeth P. B. Fontes   +12 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Dicistrovirus-Host Molecular Interactions

Current Issues in Molecular Biology, 2019
Members of the family Dicistroviridae are small RNA viruses containing a monopartite positive-sense RNA genome. Dicistroviruses mainly infect arthropods, causing diseases that impact agriculture and the economy. In this chapter, we provide an overview of current and past research on dicistroviruses including the viral life cycle, viral translational ...
Reid, Warsaba, Jibin, Sadasivan, Eric, Jan   +2 more
openaire   +2 more sources