Results 111 to 120 of about 1,965,985 (318)

Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells

Journal of Virology
Abundance of essential components of double-stranded RNA (dsRNA) recognition and the subsequent interferon (IFN) response vary widely between primary human hepatocytes (PHHs) and commonly used cell culture models based on derivatives of Huh7 cells ...
Andreas Betz, Hao-En Huang, Zuguang Gu, Ombretta Colasanti, Teng-Feng Li, Jasper Hesebeck-Brinckmann, Nadine Gillich, Gnimah Eva Gnouamozi, Matthias Schlesner, Florian W. R. Vondran, Stephan Urban, Ralf Bartenschlager, Marco Binder, Volker Lohmann   +13 more
doaj   +1 more source

Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism

eLife, 2019
Nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins in plants and animals mediate intracellular pathogen sensing. Plant NLRs typically detect strain-specific pathogen effectors and trigger immune responses often linked to ...
Isabel ML Saur, Saskia Bauer, Barbara Kracher, Xunli Lu, Lamprinos Franzeskakis, Marion C Müller, Björn Sabelleck, Florian Kümmel, Ralph Panstruga, Takaki Maekawa, Paul Schulze-Lefert   +10 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Molecular Interactions Using New Technology: A Virtual Reality Gaming Platform to Visualize and Manipulate Molecules [PDF]

, 2019
The representation of complex biomolecular structures and interactions is a difficult challenge across life sciences. Researchers and students use unintuitive 2D representations to gain an intuitive understanding of 3D space and molecular interactions ...
Gaurav Chopra (4761354), Jordon, McGraw, Jonathan A Fine (7027766), Christopher Sculley (7412948), Gaurav, Chopra, Jordon McGraw (7412941), Wei Zhang (7412946), Jonathan A, Fine, Christopher, Sculley, Wei, Zhang   +9 more
core   +1 more source

Serotonin modulation of metabolism and stress response in Pseudomonas fluorescens

BMC Biology
Background Pseudomonas fluorescens is a Gram-negative bacterium with a remarkable metabolic and physiological versatility that enables it to adapt and colonize diverse ecological niches, including the human small intestine.
Barbora Waclawiková, Markus Schwalbe, Diana Ilyaskina, Semih Toptas, Nicola U. Thome, Chao Du, Somayah S. Elsayed, Anne de Jong, Gilles P. van Wezel, Sahar El Aidy   +9 more
doaj   +1 more source

PII Protein-Derived FRET Sensors for Quantification and Live-Cell Imaging of 2-Oxoglutarate

Scientific Reports, 2017
The citric acid cycle intermediate 2-oxoglutarate (2-OG, a.k.a. alpha-ketoglutarate) links the carbon and nitrogen metabolic pathways and can provide information on the metabolic status of cells. In recent years, it has become exceedingly clear that 2-OG
Jan Lüddecke, Liliana Francois, Philipp Spät, Björn Watzer, Tomasz Chilczuk, Gernot Poschet, Rüdiger Hell, Bernhard Radlwimmer, Karl Forchhammer   +8 more
doaj   +1 more source

Sinorhizobium meliloti Controls Nitric Oxide–Mediated Post-Translational Modification of a Medicago truncatula Nodule Protein

Molecular Plant-Microbe Interactions, 2015
Nitric oxide (NO) is involved in various plant-microbe interactions. In the symbiosis between soil bacterium Sinorhizobium meliloti and model legume Medicago truncatula, NO is required for an optimal establishment of the interaction but is also a signal ...
Pauline Blanquet, Liliana Silva, Olivier Catrice, Claude Bruand, Helena Carvalho, Eliane Meilhoc   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Amino acid interactions of spiropyran [PDF]

, 2008
A solution phase study was carried out to explore the interactions between the spiropyran molecule in its merocyanine zwitterionic merocyanine 'open' form and amino acids.
Dalton, Gene
core