Results 101 to 110 of about 7,519,015 (293)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Modulation by molecular interactions /

open access: yes
Current Topics in Cellular Regulation, Volume 26: Modulation by Molecular Interactions covers various aspects of biochemical regulation that were presented in the International Symposium on the Molecular Basis of Cellular Regulation held at the National ...
Ginsburg, Ann., Levine, Rodney L.
core  

The immune NIK1/RPL10/LIMYB signaling module regulates photosynthesis and translation under biotic and abiotic stresses.

open access: yesNature Communications
Photosynthesis and translation are targets of metabolic control and development in plants, yet how stress signals coordinately regulate these opposing energy-producing and consuming processes remains enigmatic.
Marco Aurélio Ferreira   +16 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Molecular Interactions

open access: yes, 2012
In a classical approach materials science is mainly dealing with interatomic interactions within molecules, without paying much interest on weak intermolecular interactions. However, the variety of structures actually is the result of weak ordering because of noncovalent interactions.
openaire   +2 more sources

Molecular Interactions in Irradiated Solids

open access: yesRadiation Research, 1958
We have studied molecular interactions in irradiated solids by examining the electron paramagnetic spectra of various molecular mixtures and by determining the effect of glutathione on the X-ray inactivation of catalase. The spectroscopic data show that direct electron transfer can occur between molecules in irradiated solids.
A, NORMAN, W, GINOZA
openaire   +3 more sources

Effector-Triggered and Pathogen-Associated Molecular Pattern-Triggered Immunity Differentially Contribute to Basal Resistance to Pseudomonas syringae

open access: yes, 2010
Pathogens induce pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and effector-triggered immunity (ETI) in plants. PAMPs are microbial molecules recognized by host plants as nonself signals, whereas pathogen effectors are evolved to ...
Lu, Haibin   +17 more
core   +1 more source

The Role of Microarray in Modern Sequencing: Statistical Approach Matters in a Comparison Between Microarray and RNA-Seq

open access: yesBioTech
Gene expression analysis is crucial in understanding cellular processes, development, health, and disease. With RNA-seq outpacing microarray as the chosen platform for gene expression, is there space for array data in future profiling?
Isaac D. Raplee   +8 more
doaj   +1 more source

Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit

open access: yesNature Communications, 2018
SAMHD1 is a critical restriction factor for HIV-1 and its antiviral activity is regulated by T592 phosphorylation. Here, Schott et al. show that the phosphatase PP2A-B55α dephosphorylates SAMHD1 during mitotic exit, rendering it antivirally active in G1 ...
Kerstin Schott   +14 more
doaj   +1 more source

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