Results 81 to 90 of about 18,661,987 (346)

Molecular Interactions in the Assembly of Coronaviruses

, 2005
This chapter describes the interactions between the different structural components of the viruses and discusses their relevance for the process of virion formation. Two key factors determine the efficiency of the assembly process: intracellular transport and molecular interactions. Many viruses have evolved elaborate strategies to ensure the swift and
de Haan, C.A.M., Rottier, P.J.M.
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Topology of molecular interaction networks [PDF]

BMC Systems Biology, 2013
Molecular interactions are often represented as network models which have become the common language of many areas of biology. Graphs serve as convenient mathematical representations of network models and have themselves become objects of study. Their topology has been intensively researched over the last decade after evidence was found that they share
Winterbach, W. (author), Van Mieghem, P. (author), Reinders, M. (author), Wang, H. (author), De Ridder, D. (author)   +4 more
openaire   +5 more sources

Natural history of Arabidopsis thaliana and oomycete symbioses [PDF]

, 2008
Molecular ecology of plant–microbe interactions has immediate significance for filling a gap in knowledge between the laboratory discipline of molecular biology and the largely theoretical discipline of evolutionary ecology.
Eric B. Holub, Holub, E. B.
core   +1 more source

1H NMR Shift of Single Molecular Water and Its Ligand Interactions in Organic Solvents [PDF]

, 2023
Loose H-bonded water named as “free water” or “confined water” plays an important role in “on water catalysis”, or on properties of lignocellulose-based composites, as well as protein-ligand binding (lock and key inhibition) and protein mediated ...
Liuqun, Gu
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Computational approaches for investigating protein-ligand interactions - towards an in-depth understanding of the dengue virus methyltransferase [PDF]

, 2013
Interactions between proteins and their ligands play crucial roles in many biological processes, such as metabolism, signaling, transport, regulation or molecular recognition. Understanding the molecular basis of protein-ligand interactions is thus of
Schmidt, Tobias Benjamin
core   +1 more source

Evaluating Causal Claims in Plant Developmental Metabolism: A When–Where–How Framework

Plants
Metabolic changes are often described as drivers of plant development even when the evidence establishes only association or a permissive requirement. This review separates biological role from causal status and evaluates claims across seven dimensions ...
Xiangfei Cheng, Yanan Zhao, Leidi Liu, Yaning Li, Ruohang Zhao, Zhiyao Yang, Xinci Hao, Zhongling Yang, Chengde Yu, Chengming Fan, Zhifang Li   +10 more
doaj   +1 more source

Seizure-Induced Potentiation of AMPA Receptor-Mediated Synaptic Transmission in the Entorhinal Cortex

Frontiers in Cellular Neuroscience, 2018
Excessive excitation is considered one of the key mechanisms underlying epileptic seizures. We investigated changes in the evoked postsynaptic responses of medial entorhinal cortex (ERC) pyramidal neurons by seizure-like events (SLEs), using the modified
Dmitry V. Amakhin, Elena B. Soboleva, Julia L. Ergina, Sergey L. Malkin, Anton V. Chizhov, Anton V. Chizhov, Aleksey V. Zaitsev, Aleksey V. Zaitsev   +7 more
doaj   +1 more source

Divide-and-conquer approach to study protein tunnels in long molecular dynamics simulations

MethodsX, 2023
Nowadays, molecular dynamics (MD) simulations of proteins with hundreds of thousands of snapshots are commonly produced using modern GPUs. However, due to the abundance of data, analyzing transport tunnels present in the internal voids of these molecules,
Carlos Sequeiros-Borja, Bartlomiej Surpeta, Igor Marchlewski, Jan Brezovsky   +3 more
doaj   +1 more source