Results 71 to 80 of about 7,519,015 (293)

Supramolecular Secondary Ion Mass Spectrometry - Revealing Molecular Surroundings and Inter-Molecular Interactions in Organic Matter [PDF]

, 2020
While supramolecular chemistry is a firmly established research field in laboratory conditions, the experimental study of non-covalent interactions, such as hydrogen bonding and piinteractions, between different molecules in chemically rich, non ...
Laetitia, Bernard, Maciej, Kawecki, Daniele, Passerone, Rowena, Crockett   +3 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

UTRme: A Scoring-Based Tool to Annotate Untranslated Regions in Trypanosomatid Genomes

Frontiers in Genetics, 2018
Most signals involved in post-transcriptional regulatory networks are located in the untranslated regions (UTRs) of the mRNAs. Therefore, to deepen our understanding of gene expression regulation, delimitation of these regions with high accuracy is ...
Santiago Radío, Santiago Radío, Rafael Sebastián Fort, Rafael Sebastián Fort, Beatriz Garat, José Sotelo-Silveira, José Sotelo-Silveira, Pablo Smircich, Pablo Smircich   +8 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Genetical genomics reveals large scale genotype-by-environment interactions in Arabisopsis thaliana [PDF]

, 2013
One of the major goals of quantitative genetics is to unravel the complex interactions between molecular genetic factors and the environment.The effects of these genotype-byenvironment interactions also affect and cause variation in gene expression.The ...
Dekter, R., Anton J. M. Peeters, Plant Ecophysiology, van den Ackerveken, A.F.J.M., Terpstra, I.R., Molecular Plant Physiology, Dep Biologie, Sub Molecular Plant Physiology, René Dekter, Plant Microbe Interactions, Sub Plant Ecophysiology, Snoek, L.B., Guido Van den Ackerveken, van den Ackerveken, G., Inez R. Terpstra, René eDekter, Peeters, A.J., L. Basten Snoek, Peeters, A.J.M., Sub Plant-Microbe Interactions, L. Basten eSnoek, Guido eVan den Ackerveken, Anton J.M. Peeters   +22 more
core   +2 more sources

Molecular Interactions Between Plants and Insect Herbivores [PDF]

, 2019
Diverse molecular processes regulate the interactions between plants and insect herbivores. Here, we review genes and proteins that are involved in plant–herbivore interactions and discuss how their discovery has structured the current standard model of ...
Reymond, Philippe, Erb, Matthias
core   +2 more sources

Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

Nature Communications, 2017
An understanding of the dynamics of drug binding and unbinding processes is important for drug discovery. Here, the authors give insights into the binding mechanism of small drug-like molecules to human Hsp90 by combining thermodynamics and kinetics ...
M. Amaral, D. B. Kokh, J. Bomke, A. Wegener, H. P. Buchstaller, H. M. Eggenweiler, P. Matias, C. Sirrenberg, R. C. Wade, M. Frech   +9 more
doaj   +1 more source