Results 71 to 80 of about 1,965,985 (318)

A new pea cadmium tolerant mutant in a unique tool for studying molecular plant-microbe interactions under cadmium stress [PDF]

open access: yes, 2004
Tsyganov VE, Belimov AA, Safronova VI, et al. A new pea cadmium tolerant mutant in a unique tool for studying molecular plant-microbe interactions under cadmium stress. In: Tikhonovich I, Lugtenberg B, Provorov N, eds.
Borisov, Alexey Y.   +9 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Molecular torsion balances for quantifying non-covalent interactions [PDF]

open access: yes, 2013
Non-covalent interactions underpin the whole of chemistry and biology, but their study is extremely difficult in complicated biological systems. This thesis presents the application of synthetic molecular balances for gaining fundamental insights into ...
Mati, Ioulia
core  

Quantifying Protein-Protein Interactions in Molecular Simulations [PDF]

open access: yes, 2019
We present simple, accurate, and efficient methods to estimate the dissociation constant Kd and the second osmotic virial coefficient B2 from molecular simulations.
Patrick K. Quoika (8163324)   +9 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Plant basal resistance: genetics, biochemistry, and impacts on plant-biotic interactions [PDF]

open access: yes, 2012
Basal resistance depends largely on a diverse range of defence mechanisms that become active upon attack by pathogens or insects. These mechanisms range from rapid stomatal closure and production of reactive oxygen species, to callose deposition and ...
Ahmad, S.   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Molecular Basis for Polyketide Ketoreductase-Substrate Interactions. [PDF]

open access: yes, 2020
Polyketides are a large class of structurally and functionally diverse natural products with important bioactivities. Many polyketides are synthesized by reducing type II polyketide synthases (PKSs), containing transiently interacting standalone enzymes.
Tsai, Shiou-Chuan   +11 more
core   +1 more source

UTRme: A Scoring-Based Tool to Annotate Untranslated Regions in Trypanosomatid Genomes

open access: yesFrontiers in Genetics, 2018
Most signals involved in post-transcriptional regulatory networks are located in the untranslated regions (UTRs) of the mRNAs. Therefore, to deepen our understanding of gene expression regulation, delimitation of these regions with high accuracy is ...
Santiago Radío   +8 more
doaj   +1 more source

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