This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He +2 more
wiley +1 more source
AND‐Logic‐Gated Aptamer Switch for Precise Targeting and Regulation of RNA G‐Quadruplexes
An AND‐logic‐gated aptamer switch enables tumor‐selective activation of RNA G‐quadruplex (rG4)‐targeting function. By combining cell‐surface recognition and intracellular redox sensing, the system achieves precise regulation of disease‐relevant RNA structures exclusively in tumor cells, with minimal off‐target effects in normal cells, offering a ...
Dan Wang, Ying Feng, Chun Kit Kwok
wiley +2 more sources
Material‐Based Intelligence: Autonomous Adaptation and Embodied Computation in Physical Substrates
This perspective formulates a unifying framework for Material‐Based Intelligence (MBI), defining the physical requirements for materials to achieve embodied action, active memory and embodied information processing through intrinsic nonequilibrium dynamics. The design of intelligent materials often draws parallels with the complex adaptive behaviors of
Vladimir A. Baulin +4 more
wiley +1 more source
Reset-free DNA logic circuits for real-time input processing and memory. [PDF]
Sim J +8 more
europepmc +1 more source
Enzyme-driven triplex structure-based DNA logic circuits. [PDF]
Liu X +14 more
europepmc +1 more source
Intelligent molecular logic computing toolkits: nucleic acid-based construction, functionality, and enhanced biosensing applications. [PDF]
Hu Y +5 more
europepmc +1 more source
Smart control of CAR-T cells: emerging strategies for safer and more effective cancer immunotherapy. [PDF]
Zhang GK, Wang HM, Zhou F.
europepmc +1 more source
Dynamic Decoration of DNA Scaffolds for High-Resolution Cancer Cell Subtyping. [PDF]
Hu X +15 more
europepmc +1 more source
DNA computing function switching by programming base stacking interactions with minimal molecular architecture changes. [PDF]
Zhang Y +9 more
europepmc +1 more source
Twist Engineering of Hybrid 2D van der Waals‐Transition Metal Oxide Membranes
The integration of transition metal oxide membranes with 2D van der Waals materials offers exciting opportunities to study new interfacial phenomena. These interactions can create complex moiré patterns that change the materials' properties. Understanding these interactions, influenced by symmetry and distortion, poses significant challenges and ...
Mar Garcia Hernandez +4 more
wiley +1 more source

