Results 121 to 130 of about 1,994,871 (347)

Supplementary Figure 3A-C from Hypoxia-Inducible Protein 2 (<i>HIG2</i>), a Novel Diagnostic Marker for Renal Cell Carcinoma and Potential Target for Molecular Therapy

, 2023
Akira Togashi, Toyomasa Katagiri, Shingo Ashida, Tomoaki Fujioka, Osamu Maruyama, Yoshiaki Wakumoto, Yoshiro Sakamoto, Μakoto Fujime, Yoshio Kawachi, Taro Shuin, Yusuke Nakamura   +10 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Supplementary Tables 1 - 4 from Molecular Markers in Key Steroidogenic Pathways, Circulating Steroid Levels, and Prostate Cancer Progression

, 2023
Éric Lévesque, Shu‐Pin Huang, Étienne Audet‐Walsh, Louis Lacombe, Bo‐Ying Bao, Yves Fradet, Isabelle Laverdière, Mélanie Rouleau, Chao‐Yuan Huang, Chia‐Cheng Yu, Patrick Caron, Chantal Guillemette   +11 more
openalex   +1 more source

OA-183 Dynamic of molecular and resistance markers prevalence of Plasmodium falciparum during the seasonal malaria chemoprevention campaign in school aged children in Bandiagara, Mali [PDF]

, 2023
Karim Traoré, Ali Thera, Drissa Coulibaly, Abdoulaye K. Koné, S. Traoré, Kindie Kouriba, Moussa Djimdé, Guillaume Bonot, Anne‐Lise Bienvenu, Stéphane Picot, Mahamadou A. Théra   +10 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Application of next-generation sequencing in plant breeding

Czech Journal of Genetics and Plant Breeding, 2017
In the past decade, next-generation sequencing (NGS) platforms have changed the impact of sequencing on our knowledge of crop genomes and gene regulation.
David VLK, Jana ŘEPKOVÁ
doaj   +1 more source

Principal molecular markers

, 2021
Molecular markers are molecular phenotypes originating from any expressed or unexpressed segments of DNA that come from genetic inheritance and lend themselves to the differentiation of one or more individuals. It can be classified into two groups: the first, markers are obtained by hybridization and the second, markers are obtained by DNA ...
Oliveira, Altacis Junior, Oliveira, Taniele Carvalho de, Santos, Andressa Alves Cabreira dos, Siqueira, Thalyson Ade, Duarte, Willian Martins, Caldeira, Daniela Soares Alves, Vilarinho, Marcella Karoline Cardoso, Almici, Mirian da Silva, Silva, Gustavo Ferreira da, Barelli, Marco Antonio Aparecido, Karsburg, Isane Vera   +10 more
openaire   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Molecular marker v1

, 2019
SSR and SRAP markers were employed to assess the genetic diversity and structure of sixty-four samples from four populations ofEmmenopterys henryi. Twelve pairs of SRAP primers generated 86 bands, and polymorphism rate was 88.37%. 148 polymorphic alleles were detected by ten pairs of SSR primers, with an average number of polymorphic alleles per primer
Yanli Niu, Yansong Peng, Wenxing Chen, Wenxing Chen, Sadaruddin Chachar, Pingxian Zhang, Saixia Zhou, Yuan Gao   +7 more
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source