Results 111 to 120 of about 6,997,513 (404)

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Detecting bio-markers in habitable-zone earths transiting white dwarfs [PDF]

open access: yes, 2013
The characterization of the atmospheres of habitable-zone Earth-mass exoplanets that transit across main-sequence stars, let alone the detection of bio-markers in their atmospheres, will be challenging even with future facilities. It has been noted that white dwarfs (WDs) have long-lived habitable zones and that a large fraction of WDs may host planets.
arxiv   +1 more source

Detection of genetic diversity among Indian strains of _Xanthomonas campestris_ pv. _mangiferaeindicae_ using PCR-RAPD [PDF]

open access: yes, 2008
The randomly amplified polymorphic DNA (RAPD) technique was used to investigate the genetic diversity in 6 strains of _Xanthomonas campestris_ pv. _mangiferaeindicae_ (_Xcmi_), the causal pathogen of mango bacterial canker disease (MBCD).
Ram Kishun, Vijai Kumar Gupta
core   +1 more source

A multiplex oligonucleotide ligation-PCR as a complementary tool for subtyping of Salmonella Typhimurium [PDF]

open access: yes, 2015
Subtyping below the serovar level is essential for surveillance and outbreak detection and investigation of Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) and its monophasic variant 1,4,[5],12:i:- (S.
Bertrand, Sophie   +5 more
core   +2 more sources

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Zinc oxide Nanoparticles, Biosynthesis, characterization and their potent photocatalytic degradation, and antioxidant activities

open access: yesJournal of King Saud University: Science, 2023
Objectives: This study aimed to biosynthesize zinc oxide nanoparticles (ZnO-NPs) using the seed extract of Moringa oleifera. The catalytic activity of the biosynthesized ZnO-NPs was examined as photocatalyst for the degradation methylene blue (MB) and ...
Fawziah M. Albarakaty   +5 more
doaj  

GENETIC MARKERS: COMPARATIVE CLASSIFICATION OF MOLECULAR MARKERS

open access: yesОвощи России, 2018
With the creation of the molecular markers allowing to carry out analysis of genotypes on the level initial genetic information – DNA, onset one of the most multifarious and one of the most large in number class of markers at the present day.
Yu. V. Chesnokov
doaj   +1 more source

Analysis of genetic diversity among some Iraqi durum wheat cultivars revealed by different molecular markers [PDF]

open access: yes
Durum wheat has been cultivated since the beginning of crop domestication, occupying now the tenth ranking among the global most significant cultivated crops. Despite the fact that, the extent of the crop genetic diversity has not yet fully incorporated into modern varieties through breeding programs.
arxiv   +1 more source

Resistance to bleomycin increases the chronological life of cells [PDF]

open access: yes, 2019
The identification of genes involved in chronological aging could have a potential utility as molecular markers in the chemotherapy treatment of cancer.
Burgos-Molina, Antonio Manuel   +3 more
core  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

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