Results 131 to 140 of about 6,997,513 (404)

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Precision seed certification through machine learning

open access: yesTechnology in Agronomy
Original and pure seeds are the most important factors for sustainable agricultural production, development, and food security. Conventionally, seed protection and certification programs are carried out on several classes from breeders to certify seed ...
Akram Ghaffari
doaj   +1 more source

Models of Innate Neural Attractors and Their Applications for Neural Information Processing [PDF]

open access: yesarXiv, 2015
In this work we reveal and explore a new class of attractor neural networks, based on inborn connections provided by model molecular markers, the molecular marker based attractor neural networks (MMBANN). We have explored conditions for the existence of attractor states, critical relations between their parameters and the spectrum of single neuron ...
arxiv  

Molecular Markers: an Introduction and Applications

open access: yes, 2015
The dramatic development of molecular genetics has laid the groundwork for genomics. It has introduced new generations of molecular markers for use in the genetic improvement of farm animals.
F. Al-Samarai, A. Al-kazaz
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Designing the statistically optimal drug for cancer therapy [PDF]

open access: yesarXiv, 2013
Cancer and healthy cells have distinct distributions of molecular properties and thus respond differently to drugs. Cancer drugs ideally kill cancer cells while limiting harm to healthy cells. However, the inherent variance among cells in both cancer and healthy cell populations increases the difficulty of selective drug action.
arxiv  

Selection for cacao resistance to Moniliasis assisted by molecular markers [PDF]

open access: yes, 2011
The basidiomycete Moniliophthora roreri, the causal agent of moniliasis, occurs in many cocoa producer countries in South and Central Americas, but not yet in Brazil.
Clément, Didier   +4 more
core  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

A comprehensive analysis of candidate genes in familial pancreatic cancer families reveals a high frequency of potentially pathogenic germline variants

open access: yesEBioMedicine, 2020
Background: The 5-year survival rate of patients with pancreatic ductal adenocarcinoma (PDAC) is around 5% due to the fact that the majority of patients present with advanced disease that is treatment resistant. Familial pancreatic cancer (FPC) is a rare
Julie Earl   +19 more
doaj  

Improving the Efficiency of Genomic Selection [PDF]

open access: yesStatistical Applications in Genetics and Molecular Biology 2013, 12(4), 517-527, 2013
We investigate two approaches to increase the efficiency of phenotypic prediction from genome-wide markers, which is a key step for genomic selection (GS) in plant and animal breeding. The first approach is feature selection based on Markov blankets, which provide a theoretically-sound framework for identifying non-informative markers.
arxiv  

Home - About - Disclaimer - Privacy