Results 91 to 100 of about 4,145,178 (349)

Structures and genetic information of control region in mitogenomes of Odonata

Mitochondrial DNA. Part B. Resources
Mitogenome data of Odonata is accumulating and widely used in phylogenetic analysis. However, noncoding regions, especially control region, were usually omitted from the phylogenetic reconstruction.
Bin Jiang, Yu Yao, Jia Li, Jiang Zhang, Yang Sun, Shulin He   +5 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Structure formation in active networks

, 2011
Structure formation and constant reorganization of the actin cytoskeleton are key requirements for the function of living cells. Here we show that a minimal reconstituted system consisting of actin filaments, crosslinking molecules and molecular-motor ...
A Lau, Andreas R. Bausch, BD Hoffman, D Smith, D Vignjevic, DA Fletcher, DA Weitz, F Backouche, F Gallet, F Juelicher, GH Koenderink, IS Aranson, J-F Joanny, J-F Joanny, JA Spudich, JC Crocker, JC Effler, JS Langer, K Kruse, KM Schmoller, L LeGoff, LW Janson, MMAE Claessens, O Lieleg, PM Bendix, R Metzler, R Metzler, RE Kane, S MacLean-Fletcher, Simone Köhler, SS Margossian, T Guerin, T Viscek, TB Liverpool, TB Liverpool, Volker Schaller   +35 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Enhancing homology-directed repair efficiency with HDR-boosting modular ssDNA donor

Nature Communications
Despite the potential of small molecules and recombinant proteins to enhance the efficiency of homology-directed repair (HDR), single-stranded DNA (ssDNA) donors, as currently designed and chemically modified, remain suboptimal for precise gene editing ...
Ying-Ying Jin, Peng Zhang, Le-Le Liu, Xiang Zhao, Xiao-Qing Hu, Si-Zhe Liu, Ze-Kun Li, Qian Liu, Jian-Qiao Wang, De-Long Hao, Zhu-Qin Zhang, Hou-Zao Chen, De-Pei Liu   +12 more
doaj   +1 more source

Lichens: A promising source of anti-cancerous activity and their molecular mechanisms

, 2023
Monika Thakur, Bharat Kapoor, Dhriti Kapoor, Neeta Raj Sharma   +3 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Effect of Funneliformis mosseae and Cu Additives on the Astragalus sinicus Root Growth and Cd Uptake Under the Modeled Conditions

Microorganisms
Cadmium (Cd) contamination in soil poses a serious threat to plant growth and productivity, while arbuscular mycorrhizal (AM) fungi play a vital role in enhancing plant growth, improving tolerance to heavy metals, and restoring polluted ecosystems.
Yuxin Li, Rui Cai, Jindian Hu, Hongling Liu, Xiancan Zhu   +4 more
doaj   +1 more source

Effects of CYP3A4 Polymorphisms on Drug Addiction Risk Among the Chinese Han Population

Frontiers in Public Health, 2019
Background:Cytochrome P450 3A4 (CYP3A4) regulates pharmacokinetic and pharmacodynamic interactions during the process of drug absorption and metabolism, suggesting CYP3A4 plays an important role in drug addiction.
Li Wang, Li Wang, Mei Bai, Mei Bai, Tianbo Jin, Tianbo Jin, Jianwen Zheng, Jianwen Zheng, Yuhe Wang, Yuhe Wang, Yongjun He, Yongjun He, Dongya Yuan, Dongya Yuan, Xue He, Xue He   +15 more
doaj   +1 more source

Current-Driven Conformational Changes, Charging and Negative Differential Resistance in Molecular Wires

, 2001
We introduce a theoretical approach based on scattering theory and total energy methods that treats transport non-linearities, conformational changes and charging effects in molecular wires in a unified way.
A. I. Yanson, C. P. Collier, D. Sánchez-Portal, E. Emberly, E. Emberly, E. G. Emberly, Eldon G. Emberly, George Kirczenow, H. Ness, H. Ohnishi, J. Chen, J. Gaudioso, J. K. Gimzewski, L. E. Hall, M. A. Reed, M. Di Ventra, N. D. Lang, S. Datta, S. N. Yaliraki, S. P. McGlynn, W. Kohn, W. P. Su   +21 more
core   +1 more source