Results 151 to 160 of about 4,001,392 (250)

Ribosomal Proteins and Human Diseases: Pathogenesis, Molecular Mechanisms, and Therapeutic Implications

, 2014
Wei Wang, Subhasree Nag, Xu Zhang, Ming‐Hai Wang, Hui Wang, Jianwei Zhou, Ruiwen Zhang   +6 more
openalex   +2 more sources

The molecular mechanism of traditional Chinese medicine in the treatment of oropharyngeal candidiasis (OPC). [PDF]

J Oral Microbiol
Wang S, Wang H, Wei W, Wang T.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Proteoglycans remodeling in cancer: Underlying molecular mechanisms

, 2017
Achilleas D. Theocharis, Nikos K. Karamanos   +1 more
openalex   +2 more sources

ADNP: in search for molecular mechanisms and innovative therapeutic strategies for frontotemporal degeneration [PDF]

, 2015
Illana Gozes, Yanina Ivashko‐Pachima
openalex   +1 more source

Molecular and cellular mechanisms of ageing: modern knowledge (literature review)

, 2023
Р. К. Михеев, Е. Н. Андреева, O. R. Grigoryan, E. V. Sheremetyeva, Yu. S. Absatarova, A. S. Odarchenko, O. N. Opletaeva   +6 more
openalex   +2 more sources

Molecular Mechanism of ATP Hydrolysis Catalyzed by p97: A QM/MM Study. [PDF]

J Chem Theory Comput
Szántó JK, Hulm A, Ochsenfeld C.
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1

, 2016
Nikolai Hentze, Laura Le Breton, Jan Wiesner, Georg Kempf, Matthias P. Mayer   +4 more
openalex   +1 more source

Exploring the molecular mechanism of apigenin in treating bronchiectasis based on network pharmacology and molecular docking. [PDF]

Sci Rep
Huang H, Han J, Liu Y, Zhang Q, Zhou Y, Zheng S, Zhou C, Bao C, Qing C, Lu W, Wu X, Jiang Y, Zhang L, Luo J, Kong J.   +14 more
europepmc   +1 more source