Results 11 to 20 of about 2,356,701 (268)
The role of pharmacology in anticancer drug development
ADMET and DMPK, 2018 Drug development consists of many sequential and parallel steps; failure in one of the steps can lead to discontinuation of the process. The process is time-consuming and very expensive, especially the clinical phase.
Godefridus J. Peters +3 more
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Molecular mechanisms of etoposide
EXCLI journal, 2015 EXCLI Journal ; Vol.
Montecucco A, Zanetta F, Biamonti G
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Molecular mechanisms of luteinization [PDF]
Obstetrics & Gynecology Science, 2014 Dynamic changes in steroidogenesis occur in ovarian granulosa cells during ovulation after the LH surge. The ovulatory LH surge induces rapid up-regulation of steroidogenic acute regulatory (StAR) protein and rapid down-regulation of aromatase (Cyp19a1) in granulosa cells undergoing luteinization during ovulation.
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IL‐7R gene polymorphisms among patients with rheumatoid arthritis: A case–control study
Molecular Genetics & Genomic Medicine, 2019 Background Rheumatoid arthritis (RA) is the most common inflammatory disease which refers to bony erosions and joint destruction largely caused by genetic factors.
Mei Bai +5 more
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Molecular mechanism of preconditioning [PDF]
IUBMB Life, 2008 AbstractDuring the last 20 years, since the appearance of the first publication on ischemic preconditioning (PC), our knowledge of this phenomenon has increased exponentially. PC is defined as an increased tolerance to ischemia and reperfusion induced by previous sublethal period ischemia.
Manika, Das, Dipak K, Das
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The genetic polymorphisms of ZC3HC1 and SMARCA4 are associated with hypertension risk
Molecular Genetics & Genomic Medicine, 2019 Aim In this study, we aimed to evaluate the association between genetic variants of ZC3HC1 and SMARCA4 and hypertension risk in the Chinese Han population.
Huijun Ma +6 more
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Molecules, 2021 Bacteria contain glycerol phosphate (GroP)-containing glycans, which are important constituents of cell-surface glycopolymers such as the teichoic acids of Gram-positive bacterial cell walls.
Rieko Imae, Hiroshi Manya, Tamao Endo
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Molecular mechanisms of fibrinolysis [PDF]
British Journal of Haematology, 2005 SummaryThe molecular mechanisms that finely co‐ordinate fibrin formation and fibrinolysis are now well defined. The structure and function of all major fibrinolytic proteins, which include serine proteases, their inhibitors, activators and receptors, have been characterized.
Gabriela, Cesarman-Maus +1 more
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Digital twin in healthcare: Recent updates and challenges
Digital Health, 2023 As simulation is playing an increasingly important role in medicine, providing the individual patient with a customised diagnosis and treatment is envisaged as part of future precision medicine.
Tianze Sun, Xiwang He, Zhonghai Li
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Identification of quiescent FOXC2+ spermatogonial stem cells in adult mammals
eLife, 2023 In adult mammals, spermatogenesis embodies the complex developmental process from spermatogonial stem cells (SSCs) to spermatozoa. At the top of this developmental hierarchy lie a series of SSC subpopulations.
Zhipeng Wang +19 more
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