Results 31 to 40 of about 8,494,354 (311)

Molecular Mechanisms of Preeclampsia [PDF]

open access: yesJournal of Pregnancy, 2012
Preeclampsia is one of the leading causes of maternal morbidity/mortality. The pathogenesis of preeclampsia is still under investigation. The aim of this paper is to present the molecular mechanisms implicating in the pathway leading to preeclampsia.
N. Vitoratos, D. Hassiakos, C. Iavazzo
openaire   +3 more sources

Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations [PDF]

open access: yes, 2011
Computer simulation of protein dynamics offers unique high-resolution information that complements experiment. Using experimentally derived structures of the natively folded prion protein (PrP), physically realistic dynamics and conformational changes ...
Valerie Daggett   +3 more
core   +1 more source

Molecular Mechanism of Microbiota Metabolites in Preterm Birth: Pathological and Therapeutic Insights

open access: yes, 2021
Preterm birth (PTB) refers to the birth of infants before 37 weeks of gestation and is a challenging issue worldwide. Evidence reveals that PTB is a multifactorial dysregulation mediated by a complex molecular mechanism.
Youngju Kim   +4 more
core   +1 more source

IL‐7R gene polymorphisms among patients with rheumatoid arthritis: A case–control study

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Rheumatoid arthritis (RA) is the most common inflammatory disease which refers to bony erosions and joint destruction largely caused by genetic factors.
Mei Bai   +5 more
doaj   +1 more source

Molecular mechanisms of lidocaine

open access: yesAnnals of Medicine & Surgery, 2021
Lidocaine is an amide-class local anesthetic used clinically to inhibit pain sensations. Systemic administration of lidocaine has antinociceptive, antiarrhythmic, anti-inflammatory, and antithrombotic effects. Lidocaine exerts these effects under both acute and chronic pain conditions and acute respiratory distress syndrome through mechanisms that can ...
Karnina, Resiana   +3 more
openaire   +2 more sources

An Asymmetric Mechanism in a Symmetric Molecular Machine [PDF]

open access: yes, 2020
The design of molecular architectures exhibiting functional motions is a promising area for disruptive technological development. Towards this goal, rotaxanes and catenanes, which undergo relative motions of their sub-units in response to external ...
Florian, Blanc   +9 more
core   +1 more source

The molecular origin of the OCP-dependent non-photochemical quenching mechanism in cyanobacteria [PDF]

open access: yes, 2022
Cyanobacteria were the first microorganisms that released oxygen into the atmosphere billions of years ago. To do it safely under intense sunlight, they developed strategies that prevent photooxidation in the photosynthetic membrane.
Fernando, Muzzopappa   +5 more
core   +1 more source

The genetic polymorphisms of ZC3HC1 and SMARCA4 are associated with hypertension risk

open access: yesMolecular Genetics & Genomic Medicine, 2019
Aim In this study, we aimed to evaluate the association between genetic variants of ZC3HC1 and SMARCA4 and hypertension risk in the Chinese Han population.
Huijun Ma   +6 more
doaj   +1 more source

Biosynthetic Mechanisms and Biological Significance of Glycerol Phosphate-Containing Glycan in Mammals

open access: yesMolecules, 2021
Bacteria contain glycerol phosphate (GroP)-containing glycans, which are important constituents of cell-surface glycopolymers such as the teichoic acids of Gram-positive bacterial cell walls.
Rieko Imae, Hiroshi Manya, Tamao Endo
doaj   +1 more source

Digital twin in healthcare: Recent updates and challenges

open access: yesDigital Health, 2023
As simulation is playing an increasingly important role in medicine, providing the individual patient with a customised diagnosis and treatment is envisaged as part of future precision medicine.
Tianze Sun, Xiwang He, Zhonghai Li
doaj   +1 more source

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