Results 311 to 320 of about 4,304,368 (356)
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Molecular mechanisms of immunosuppression
Journal of Autoimmunity, 1992The immunosuppressive drug cyclosporin A (CsA, Sandimmun, SIM) is currently being evaluated in a variety of autoimmune disorders with some remarkable successes. Despite the wide empiric application of CsA, the precise mechanism of action of this drug remains elusive.
G, Baumann +6 more
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Molecular mechanisms of photocarcinogenesis
Frontiers in Bioscience, 2002Photocarcinogenesis represents the accumulation of genetic changes as well as immune system modulation, which ultimately lead to the development of skin cancers. The recent advances in molecular and cellular biology have clarified the mechanisms of photocarcinogenesis, including the formation of DNA photoproducts, DNA repair, mutation of proto ...
Yasuhiro, Matsumura +1 more
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Molecular Mechanisms of Oncogenesis
1990Cellular oncogenes (c-oncs) have been highly conserved throughout evolution and subserve important roles in growth and development. Both in development and the neoplastic state, c-oncs appear to collaborate rather than function independently. Cellular oncogenes are activated in the neoplastic process by four (nonviral) mechanisms; (a) chromosomal ...
T A, Seemayer, W K, Cavenee
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Molecular Mechanisms of Lymphangiogenesis
International Journal of Hematology, 2004Although the process of vascular development has been well documented, little is understood about lymphatic vasculature formation, despite its importance in normal and pathologic conditions. The dysfunction or abnormal growth of lymphatic vessels is associated with lymphedema and cancer metastasis. The recent discovery of lymphangiogenic growth factors
Meiko, Takahashi +2 more
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Molecular mechanisms of cholestasis
Wiener Medizinische Wochenschrift, 2006Recent progress has enhanced our understanding of the pathogenesis of cholestatic liver diseases. Mutations in genes encoding for hepatobiliary transport systems can cause hereditary cholestatic syndromes and exposure to cholestatic agents (drugs, hormones, inflammatory cytokines) can lead to reduced expression and function of hepatic uptake and ...
Gernot, Zollner, Michael, Trauner
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Molecular mechanisms of photosensitization
Biochimie, 1986The first part of this article is devoted to basic concepts of photosensitization and to the primary photophysical and photochemistry processes involved in the reaction. The electronic configuration of molecular oxygen in its ground or activated states, which intervene in numerous photosensitized reactions, is reviewed.
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Molecular mechanisms of forgetting
European Journal of Neuroscience, 2020Abstract The field of learning and memory has largely focused their efforts on memory formation, deeming the act of forgetting as a necessary and unavoidable error of the brain's storage system. However, recent studies show that forgetting might be a purposeful mechanism with dedicated molecular pathways.
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Mechanisms: molecular machines
Current Opinion in Chemical Biology, 2011Stephen J, Benkovic, Kevin D, Raney
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Molecular Mechanisms of Amphetamines
2019There is a plethora of amphetamine derivatives exerting stimulant, euphoric, anti-fatigue, and hallucinogenic effects; all structural properties allowing these effects are contained within the amphetamine structure. In the first part of this review, the interaction of amphetamine with the dopamine transporter (DAT), crucially involved in its behavioral
Maarten E A, Reith, Margaret E, Gnegy
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Seminars in nephrology, 2000
The clinically useful and potent distal acting diuretics enhance urinary NaCl excretion by specific inhibition of distinct sodium transport processes in the loop of Henle and distal nephron. When these compounds were first used as diuretics little was known about their cellular mechanisms of action.
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The clinically useful and potent distal acting diuretics enhance urinary NaCl excretion by specific inhibition of distinct sodium transport processes in the loop of Henle and distal nephron. When these compounds were first used as diuretics little was known about their cellular mechanisms of action.
openaire +1 more source