Results 111 to 120 of about 3,444,468 (295)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
iScienceSummary: Cerebrospinal fluid (CSF) samples are commonly collected via lumbar puncture (LP) in both clinical and research settings for measurement of biomarkers of Alzheimer’s disease (AD). To determine the effects of LP on CSF AD biomarkers, we collected
Jianglei Xu +14 more
doaj +1 more source
Brazilian Journal of Psychiatry, 2012 Psychiatric disorders are among the most common human illnesses; still, the molecular and cellular mechanisms underlying their complex pathophysiology remain to be fully elucidated.
Debora Marques de Miranda +12 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Assessing traditional Chinese medicine from a molecular perspective
Journal of Traditional Chinese Medical SciencesMolecular medicine, which delves into the intricacies of biomolecular structure, function, and role, is pivotal for advancing precise diagnostics and personalized treatment.
Minhui Su +4 more
doaj +1 more source
New Advances in Gastroenterology: The Crucial Role of Molecular Medicine. [PDF]
Int J Mol Sci, 2023 Candelli M, Franceschi F.
europepmc +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Molecular Medicine Select [PDF]
Cell, 2008 Small noncoding RNAs, including endogenous antisense RNAs and microRNAs, are involved in many different cellular processes. This issue's Molecular Medicine Select highlights recent work investigating the roles of these RNAs in various aspects of tumorigenesis, suggesting new prognostic, and possibly therapeutic, tools for treating cancer.
openaire +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Editorial of the Special Issue "Molecular Medicine Applications in Infectious Diseases: Latest Innovations". [PDF]
Int J Mol Sci, 2023 Hassan STS.
europepmc +1 more source