Results 131 to 140 of about 1,085,190 (301)

Microbiome analysis in Asia’s largest watershed reveals inconsistent biogeographic pattern and microbial assembly mechanisms in river and lake systems

iScience
Summary: Microorganisms are critical to the stability of aquatic environments, and understanding the ecological mechanisms of microbial community is essential.
Xi Liu, Lu Zhang, Yingcai Wang, Sheng Hu, Jing Zhang, Xiaolong Huang, Ruiwen Li, Yuxin Hu, Huaiying Yao, Zhi Wang   +9 more
doaj   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

Advanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du   +12 more
wiley   +1 more source

Transcriptomic and proteomic analysis reveals the mechanism of chicken cecum response to Salmonella enterica serovar Enteritidis inoculation

iScience
Summary: Salmonella enterica serovar Enteritidis (SE) incurs foodborne illnesses and poses a severe threat to poultry industry and human health. However, the molecular mechanisms underlying chicken responding to SE inoculation remain elusive.
Yuanmei Wang, Liying Liu, Yanan Zhao, Yanru Ren, Xiuxiu Miao, Yaning Dong, Lewen Liu, Xianyao Li   +7 more
doaj   +1 more source

High-Affinity Phosphate-Binding Protein (PBP) For Phosphorous Recovery: Proof of Concept Using Recombinant \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2016
Phosphorus (P) is a critical, non-renewable nutrient; yet excess discharges can lead to eutrophication and deterioration of water quality. Thus, P removal from water must be coupled with P recovery to achieve sustainable P management. P-specific proteins
Ballent, Wendy, Mayer, Brooke, Yang, Yu
core   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

Advanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu, Weize Xu, Da Lin, Leqiang Sun, Jinxia Dai, Gang Cao   +5 more
wiley   +1 more source

Infection and resistance mechanisms of phage vB_VpM-PP270 in Vibrio parahaemolyticus via capsular polysaccharide

iScience
Summary: Vibrio parahaemolyticus is a major foodborne pathogen that threatens public health and aquaculture, necessitating alternative biocontrol strategies such as phage therapy.
Zhu Xihui, Hong Junshan, Xu Jiayin, Tang Luqi, Li Pei, Jiang Wei, Zhang Wei   +6 more
doaj   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Molecular microbiology

, 2021
Tran, Nam, Whitman, Jeffrey
openaire   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

Advanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu, Hang Li, Peng Liu, Zhe Jiao, Ding Zhang, Zhelin Su, Sai Niu, Jintao Zhang, Yuejun Shi, Guiqing Peng   +9 more
wiley   +1 more source

The sequence of events of enteropathogenic E. coli’s type III secretion system translocon assembly

iScience
Summary: Many bacterial pathogens employ the type III secretion system (T3SS), a specialized complex that transports effector proteins that manipulate various cellular processes.
Jenia Gershberg, May Morhaim, Irina Rostrovsky, Jerry Eichler, Neta Sal-Man   +4 more
doaj   +1 more source