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Applications of molecular microbiology to vaccinology
The Lancet, 1997Genetics, cell biology, and whole-genome sequencing of pathogens have changed dramatically the opportunities to investigate the epidemiology, pathogenesis, diagnosis, and control of microbial diseases. For example, recombinant DNA and PCR are powerful tools used to isolate genes whose role in pathogenicity can be investigated in biologically relevant ...
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Quality in the Molecular Microbiology Laboratory
2012In the clinical microbiology laboratory advances in nucleic acid detection, quantification, and sequence analysis have led to considerable improvements in the diagnosis, management, and monitoring of infectious diseases. Molecular diagnostic methods are routinely used to make clinical decisions based on when and how to treat a patient as well as ...
Paul S, Wallace, William G, MacKay
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Stains in microbiology and molecular biology
Biotechnic & Histochemistry, 2001H. J. Conn of the New York Agricultural Experiment Station was the founder and leader of the Commission on the Standardization of Biological Stains. This Commission ultimately evolved into the present Biological Stain Commission. Conn did much to determine the chemistry of stains and to promote their applications in biology.
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Molecular genetics, microbiology, and prehistory
BioEssays, 1988In this brief article, Davis outlined six possible reasons that the discovery by Avery and his colleagues was "taken for granted" by many in the scientific community, and specifically, by the Nobel Committee.
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Application of Molecular Microbiology
2014Biofilm is an aggregate of microorganisms with a distinct architecture where cells stick to a static surface. These cells are embedded with the self-produced matrix that consists of extracellular polymeric substances (EPS). These EPS consist of extracellular deoxyribonucleic acid (DNA), proteins and polysaccharides. Biofilm may be formed on both living
Surajit Das, Hirak Ranjan Dash
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Molecular microbiology methods for environmental diagnosis
Environmental Chemistry Letters, 2016To reduce the environmental footprint of human activities, the quality of environmental media such as water, soil and the atmosphere should be first assessed. Microorganisms are well suited for a such assessment because they respond fast to environmental changes, they have a huge taxonomic and genetic diversity, and they are actively involved in ...
Bouchez, Théodore +22 more
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Preanalytical Challenges of Molecular Microbiology Tests
Clinics in Laboratory MedicineAs infectious disease diagnostics increasingly incorporates molecular techniques, there are unique preanalytical concerns that must be considered. First, noninvasive specimen types that may be inadequate for culture-based diagnostics may be acceptable when using molecular tests.
Anisha, Misra, Eleanor A, Powell
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Computational microbiology of bacteria: Advancements in molecular dynamics simulations
Structure, 2023Dheeraj Prakaash +2 more
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