A virus-induced molecular mimicry model of multiple sclerosis [PDF]
Julie K. Olson+4 more
openalex +1 more source
PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao+14 more
wiley +1 more source
IgA cross-reactivity between a nuclear autoantigen and wheat proteins suggests molecular mimicry as a possible pathomechanism in celiac disease [PDF]
Susanne Natter+8 more
openalex +1 more source
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope+13 more
wiley +1 more source
Efficient imaging and computer vision detection of two cell shapes in young cotton fibers
Abstract Premise The shape of young cotton (Gossypium) fibers varies within and between commercial cotton species, as revealed by previous detailed analyses of one cultivar of G. hirsutum and one of G. barbadense. Both narrow and wide fibers exist in G. hirsutum cv.
Benjamin P. Graham+5 more
wiley +1 more source
ABO System: molecular mimicry of Ascaris lumbricoides
A. lumbricoides has been associated to the ABO System by various authors. The objective was to detect ABO System epitopes in A. lumbricoides of groups O, A, B and AB patients.
Ponce de León Patricia, Valverde Juana
doaj
Lupus anti-DNA autoantibodies cross-react with a glomerular structural protein: a case for tissue injury by molecular mimicry [PDF]
Gustavo Mostoslavsky+7 more
openalex +1 more source
Molecular mimicry and immune thrombocytopenia
In this issue of Blood, Zhang and colleagues show evidence that many thrombocytopenic patients infected with HCV have autoantibodies specific for a defined peptide sequence in platelet membrane glycoprotein IIIa. These autoantibodies appear to be the result of an immune response mounted against one or more peptides present in the HCV core envelope ...
openaire +3 more sources
Engineering the Immune Response to Biomaterials
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam+12 more
wiley +1 more source
Molecular mimicry and autoimmune liver disease: virtuous intentions, malign consequences [PDF]
Dimitrios P. Bogdanos+2 more
openalex +1 more source