Results 211 to 220 of about 3,245,847 (271)

Downsizing the Histone H3–H4 Quaternary Structure Into Foldamer Mimetics Yields High‐Affinity and Cell‐Permeable Ligands of ASF1

Angewandte Chemie, EarlyView.
We present a foldamer strategy to downsize the histone H3‐H4 quaternary structure into high‐affinity, medium‐sized binders (∼2 kDa) for the histone chaperone ASF1. Our peptide‐oligourea chimeras, designed through structure‐guided optimization and foldamer chemistry, recapitulate the natural H3‐H4 dimer binding mode while demonstrating plasma stability ...
Bo Li, Marie E. Perrin, Emma Maillard, Arthur Vitard, Gwenaëlle Moal, Johanne Mbianda, Christophe André, Magda Teixeira Nunes, Marie Vandamme, Guillaume Pinna, Céline Douat, Emmanuelle Thinon, Raphaël Guerois, Pierre Legrand, Gilles Guichard, Francoise Ochsenbein   +15 more
wiley   +1 more source

Mapping the global research landscape on molecular mimicry: a visualization and bibliometric study. [PDF]

J Transl Med
Zyoud SH.
europepmc   +1 more source

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

Angewandte Chemie, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee, Sumin Son, Jeong Yeon Yoo, Ji Hyae Lee, Meehyun Chun, Seung Bum Park   +5 more
wiley   +1 more source

Diverse genetic conflicts mediated by molecular mimicry and computational approaches to detect them. [PDF]

Semin Cell Dev Biol
Russell SL, Penunuri G, Condon C.
europepmc   +1 more source

Record Dissymmetry in Vibrational Optical Activity: Combining Vibronic Coupling and Aggregation in Cobalt(II) Camphorate Complexes

Angewandte Chemie, EarlyView.
The cobalt(II) bis(trifluoroacetylcamphorate) scaffold exhibits versatile coordination chemistry with solvent‐driven ligand exchange and geometrical rearrangements, associated with unique chiroptical properties. Microcrystalline suspension of [Co(tfc)2(CH3CN)2] revealed the largest VCD dissymmetry factor ever reported (g ≈ 0.2 at 1600 cm−1), arising ...
Gianmarco Papi, Massimo Guelfi, Stefano Zacchini, Fabio Marchetti, Gennaro Pescitelli   +4 more
wiley   +1 more source

Bioinformatics analysis of myelin-microbe interactions suggests multiple types of molecular mimicry in the pathogenesis of multiple sclerosis. [PDF]

PLoS One
Bigdeli A, Ghaderi-Zefrehei M, Lesch BJ, Behmanesh M, Arab SS.   +4 more
europepmc   +1 more source

Single‐Atom Control of Aromaticity and Excited‐State Dynamics in Endohedral Zirconium–Antimony Zintl Clusters

Angewandte Chemie, EarlyView.
Single‐atom growth from [Zr@Sb12]2− to [Zr@Sb13]3− disrupts the closed‐shell S2P6 superatomic configuration and markedly attenuates three‐dimensional (3D) aromaticity. Ultrafast spectroscopy further links stronger spherical aromaticity to slower excited‐state relaxation, establishing an atom‐resolved structure‐aromaticity‐dynamics relationship ...
Yun Zhang, Ziqi Deng, Wen‐Juan Tian, Hui‐Qing Sun, Kang Sun, Alvaro Muñoz‐Castro, Zhong‐Ming Sun, Teng‐Teng Chen   +7 more
wiley   +1 more source

Evidence for Molecular Mimicry between SARS-CoV-2 and Human Antigens: Implications for Autoimmunity in COVID-19. [PDF]

Autoimmune Dis
Arévalo-Cortés A, Rodriguez-Pinto D, Aguilar-Ayala L.   +2 more
europepmc   +1 more source

Ambiphilic Ligand Stabilization of Aluminum(I) Fragments: Halides, Cations, and a Hydride

Angewandte Chemie, EarlyView.
Stabilization of elusive aluminum(I) halides in the framework of an ambiphilic ligand is reported. The unique bonding situation at the trigonal‐bipyramidal aluminum center is analyzed, and the coordination chemistry and Al(I)Br transfer reactivity of the complexes are presented.
Charlotte S. V. Weiß, Philipp Dabringhaus   +1 more
wiley   +1 more source

Molecular Mimicry between <i>Toxoplasma gondii</i> B-Cell Epitopes and Neurodevelopmental Proteins: An Immunoinformatic Approach. [PDF]

Biomolecules
Meza-Sosa KF, Valle-Garcia D, González-Conchillos H, Blanco-Ayala T, Salazar A, Flores I, Gómez-Manzo S, González Esquivel DF, Pérez de la Cruz G, Pineda B, Pérez de la Cruz V.   +10 more
europepmc   +1 more source