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Potential Molecular Mimicry Proteins Responsive to α-pinene in Bursaphelenchus xylophilus

International Journal of Molecular Sciences, 2020
Bursaphelenchus xylophilus is a nematode species that has damaged pine trees worldwide, but its pathogenesis has not been fully characterized. α-pinene helps protect host species during the early B. xylophilus infection and colonization stages.
Li Yongxia, Yuqian Feng
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Molecular Mimicry in Multiple Sclerosis

New England Journal of Medicine, 2003
Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.
Wekerle, H., Hohlfeld, R.
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Tropomyosin and molecular mimicry

Parasitology Today, 1991
cyst investiture in nonmuscle tropo- myosin may play a role in immune evasion in the snail host by protecting the sporocyst from amoebocyte attack. If true, this would be a prime example of molecular mimicry in its full and original sense s , which links common structures to the host-parasite relationship.
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Molecular mimicry revisited

Parasitology Today, 1987
The host immune response is an important line of defence against parasites. Tactics to evade this response are therefore expected in host-parasite relationships, and the clearest example is the antigenic variation displayed by African trypanosomes. But while few other parasites seem to have quite this ability, many seem to display a form of antigenic ...
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Molecular Mimicry and Diabetes

1989
Insulin-dependent diabetes (IDDM) often develops early in life and is associated with lifelong insulin treatment, a reduced life span, and serious long-term complications (Borch-Johnsen et al. 1986). Other forms of diabetes exist (National Diabetes Data Group 1979), e.g., noninsulin-dependent diabetes, maturity onset diabetes in the young (MODY), and ...
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Molecular Mimicry of Carbohydrates by Peptides

Australian Journal of Chemistry, 2002
The use of carbohydrates as drugs and vaccines has several limitations. Molecular mimics of carbohydrates provide an alternative source of compounds to target pathways involving protein-carbohydrate interactions. In recent years, immunological studies have demonstrated the ability of certain peptides to act as molecular mimics of carbohydrates, in that
Margaret A. Johnson, B. Mario Pinto
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Malaria and ovalocytosis — molecular mimicry?

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1991
Two recently published reports have described findings which will have a profound impact on the understanding of molecular mechanisms of human resistance to malaria infection. In Melanesian ovalocytosis, a genetic polymorphism found in Papua New Guinea and parts of South East Asia, the red cells are highly resistant to invasion by various species of ...
A, Husain-Chishti, P, Ruff
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Molecular Mimicry: Fact or Fiction?

Rheumatology, 1988
Molecular studies suggest that peptide sequence similarities are present between HLA-B27 and bacteria, but the pathological mechanisms in spondyloarthropathies remain unclear.
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Molecular mimicry in MS

Nature Immunology, 2022
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Structural Basis of Molecular Mimicry

Journal of Autoimmunity, 2001
Infectious agents are thought to play an important role in the development of autoimmune diseases. Sequence similarity between infectious agents and self-proteins (molecular mimicry) has been proposed as a mechanism for the induction of autoimmunity [1].
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