Results 61 to 70 of about 4,511,721 (218)

Autoimmunity and molecular mimicry in tropical spastic paraparesis/human T-lymphotropic virus-associated myelopathy

Brazilian Journal of Medical and Biological Research, 2005
Viruses share antigenic sites with normal host cell components, a phenomenon known as molecular mimicry. It has long been suggested that viral infections might trigger an autoimmune response by several mechanisms including molecular mimicry.
F. García-Vallejo, M.C. Domínguez, O. Tamayo   +2 more
doaj   +1 more source

From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry

Antibodies, 2020
Aim: To define the autoimmune potential of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. Methods: Experimentally validated epitopes cataloged at the Immune Epitope DataBase (IEDB) and present in SARS-CoV-2 were analyzed for ...
D. Kanduc
semanticscholar   +1 more source

Rat models of autoimmune uveitis [PDF]

, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Diedrichs-Moehring, Maria, Thurau, Stephan R., Wildner, Gerhild   +2 more
core   +1 more source

EMoMiS: A pipeline for epitope-based molecular mimicry search in protein structures with potential applications to SARS-CoV-2

Computational and Structural Biotechnology Journal
The Epitope-based Molecular Mimicry Search (EMoMiS) pipeline developed in this study provides a valuable computational tool for predicting molecular mimicry between antigens.
Vitalii Stebliankin, Rajeshwari Chellappan, Prabin Baral, Christian Balbin, Janelle Nunez-Castilla, Masrur Sobhan, Trevor Cickovski, Ashleigh N. Riegler, Ananda Mohan Mondal, Jessica Siltberg-Liberles, Prem Chapagain, Sathibalan Ponniah, Sixto M. Leal, Jr, Kalai Mathee, Giri Narasimhan   +14 more
doaj   +1 more source

Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance We have previously demonstrated an increased autoantibody reactivity to Anoctamin 2 (ANO2), an ion channel expressed in the central nervous system (CNS), in multiple sclerosis (MS).
K. Tengvall, Jesse Huang, C. Hellström, P. Kammer, Martin Biström, B. Ayoglu, I. Lima Bomfim, P. Stridh, J. Butt, N. Brenner, A. Michel, K. Lundberg, L. Padyukov, I. Lundberg, E. Svenungsson, I. Ernberg, S. Olafsson, A. Dilthey, J. Hillert, L. Alfredsson, P. Sundström, P. Nilsson, T. Waterboer, T. Olsson, I. Kockum   +24 more
semanticscholar   +1 more source

An introgressed wing pattern acts as a mating cue. [PDF]

, 2015
Heliconius butterflies provide good examples of both homoploid hybrid speciation and ecological speciation. In particular, examples of adaptive introgression have been detected among the subspecies of Heliconius timareta, which acquired red color pattern
Enciso-Romero, Juan, Jiggins, Chris D, Linares, Mauricio, Muñoz, Astrid, Pardo Díaz, Geimy Carolina, Salazar, Camilo, Sánchez, Angela P.   +6 more
core   +2 more sources

Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach

Microorganisms, 2023
Molecular mimicry, a phenomenon in which microbial or environmental antigens resemble host antigens, has been proposed as a potential trigger for autoimmune responses.
Saleh Alshamrani, Mutaib M. Mashraqi, Ahmad Alzamami, Norah A. Alturki, Hassan H. Almasoudi, Mohammed Abdulrahman Alshahrani, Zarrin Basharat   +6 more
doaj   +1 more source

Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and their Sequelae

Microbiology spectrum, 2019
The group A streptococci are associated with a group of diseases affecting the heart, brain, and joints that are collectively referred to as acute rheumatic fever.
M. Cunningham
semanticscholar   +1 more source

Müllerian mimicry as a result of codivergence between velvet ants and spider wasps.

PLoS ONE, 2014
Recent studies have delineated a large Nearctic Müllerian mimicry complex in Dasymutilla velvet ants. Psorthaspis spider wasps live in areas where this mimicry complex is found and are phenotypically similar to Dasymutilla.
Juanita Rodriguez, James P Pitts, Carol D von Dohlen, Joseph S Wilson   +3 more
doaj   +1 more source

A possible role for autoimmunity through molecular mimicry in alphavirus mediated arthritis

Scientific Reports, 2020
Alphaviral infections are foremost in causing debilitating clinical outcomes in humans characterized by rheumatic arthritis like conditions. Though the presence of virus in joints and associated inflammation has been implicated as one of the reasons for ...
Siva Sai Krishna Venigalla, Sowmya Premakumar, V. Janakiraman   +2 more
semanticscholar   +1 more source