Results 61 to 70 of about 3,774,726 (329)

Autoimmunity and molecular mimicry in tropical spastic paraparesis/human T-lymphotropic virus-associated myelopathy

open access: yesBrazilian Journal of Medical and Biological Research, 2005
Viruses share antigenic sites with normal host cell components, a phenomenon known as molecular mimicry. It has long been suggested that viral infections might trigger an autoimmune response by several mechanisms including molecular mimicry.
F. García-Vallejo   +2 more
doaj   +1 more source

Molecular mimicry: Basis for autoimmunity [PDF]

open access: yesIndian Journal of Clinical Biochemistry, 2000
Structural similarity between a viral protein and a self-component can trigger an autoimmune response, which is the basis of molecular mimicry. Alternatively an invading virus can induce an inflammatory response which in turn can initiate an attack by hitherto dormant T cells on a specific self-antigen, a phenomenon which is referred to as Bystander ...
openaire   +3 more sources

Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena?

open access: yesCell stress & chaperones (Print), 2020
It is evident that COVID-19, the disease due to severe acute respiratory syndrome coronavirus 2 (commonly abbreviated SARS-CoV-2) etiological agent, is not uniquely a respiratory disease, at least in a subset of patients.
F. Cappello
semanticscholar   +1 more source

Hydrodynamic Instabilities Provide A Generic Route To Spontaneous Biomimetic Oscillations In Chemomechanically Active Filaments [PDF]

open access: yesNature Scientific Reports, 3, 1964 (2013), 2012
Non-equilibrium processes which convert chemical energy into mechanical motion enable the motility of organisms. Bundles of inextensible filaments driven by energy transduction of molecular motors form essential components of micron-scale motility engines like cilia and flagella.
arxiv   +1 more source

Müllerian mimicry as a result of codivergence between velvet ants and spider wasps.

open access: yesPLoS ONE, 2014
Recent studies have delineated a large Nearctic Müllerian mimicry complex in Dasymutilla velvet ants. Psorthaspis spider wasps live in areas where this mimicry complex is found and are phenotypically similar to Dasymutilla.
Juanita Rodriguez   +3 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

The possible role of molecular mimicry in SARS-CoV-2-mediated autoimmunity: an immunobiochemical basis

open access: yesJournal of Medical Science, 2021
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), persists as a threat to global health and continues to be a rapidly evolving condition.
Dženan Kovačić   +2 more
doaj   +1 more source

Self-Assembly of Patchy Particles into Diamond Structures through Molecular Mimicry [PDF]

open access: yes, 2012
Fabrication of diamond structures by self-assembly is a fundamental challenge in making three-dimensional photonic crystals. We simulate a system of model hard particles with attractive patches and show that they can self-assemble into a diamond structure from an initially disordered state.
arxiv   +1 more source

Deep learning on butterfly phenotypes tests evolution's oldest mathematical model [PDF]

open access: yesSci Adv 5, eaaw4967 (2019), 2019
Traditional anatomical analyses captured only a fraction of real phenomic information. Here, we apply deep learning to quantify total phenotypic similarity across 2468 butterfly photographs, covering 38 subspecies from the polymorphic mimicry complex of $\textit{Heliconius erato}$ and $\textit{Heliconius melpomene}$.
arxiv   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

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