Results 61 to 70 of about 3,812,700 (365)

Is molecular mimicry the culprit in the autoimmune haemolytic anaemia affecting patients with COVID‐19?

open access: yesBritish Journal of Haematology, 2020
This Journal recently published two papers describing autoimmune hemolytic anemia (AIHA) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (1, 2).
F. Angileri   +5 more
semanticscholar   +1 more source

Sarcoidosis, Cancer and Molecular Mimicry [PDF]

open access: yesInternational Journal of Immunopathology and Pharmacology, 2013
Molecular mimicry seems to be the most important factor for the heterogeneous clinical presentation and the immunopathogenesis of sarcoidosis. Molecular mimicry may occur as a result of altered activity of oncogenes. This can lead to crossed-type mediated body reactions targeting structurally similar sections or regions from the tissue homeostasis ...
Uwe Wollina, Georgi Tchernev
openaire   +2 more sources

miPepBase: A Database of Experimentally Verified Peptides Involved in Molecular Mimicry

open access: yesFrontiers in Microbiology, 2017
Autoimmune diseases emerge due to several reasons, of which molecular mimicry i.e., similarity between the host's and pathogen's interacting peptides is an important reason. In the present study we have reported a database of only experimentally verified
Anjali Garg   +3 more
doaj   +1 more source

The impact of antigenic molecular mimicry on anti-cancer T-cell immune response

open access: yesFrontiers in Oncology, 2022
Individuals are exposed to intracellular pathogens (i.e. viruses and intracellular bacteria) and intestinal microbiota, collectively microorganisms (MOs), which enter the body during the host’s lifetime.
Maria Tagliamonte, Luigi Buonaguro
doaj   +1 more source

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil. [PDF]

open access: yes, 2019
Zika virus infection is associated with the development of Guillain-Barré syndrome (GBS), a neurological autoimmune disorder caused by immune recognition of gangliosides and other components at nerve membranes.
Alcantara, Luiz Carlos Junior   +7 more
core   +1 more source

Molecular Mimicry Analyses Unveiled the Human Herpes Simplex and Poxvirus Epitopes as Possible Candidates to Incite Autoimmunity

open access: yesPathogens, 2022
Clinical epidemiological studies have reported that viral infections cause autoimmune pathology in humans. Host-pathogen protein sequences and structure-based molecular mimicry cause autoreactive T cells to cross-activate.
Sara Begum   +8 more
doaj   +1 more source

From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry

open access: yesAntibodies, 2020
Aim: To define the autoimmune potential of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. Methods: Experimentally validated epitopes cataloged at the Immune Epitope DataBase (IEDB) and present in SARS-CoV-2 were analyzed for ...
D. Kanduc
semanticscholar   +1 more source

Lack of Evidence for Molecular Mimicry in HIV-Infected Subjects. [PDF]

open access: yesPLoS ONE, 2015
Previous studies in HIV patients have reported autoantibodies to several human proteins, including erythropoietin (EPO), interferon-α (IFN-α), interleukin-2 (IL-2), and HLA-DR, as potential mediators of anemia or immunosuppression.
Peter D Burbelo   +4 more
doaj   +1 more source

Benchmarking evolutionary tinkering underlying human–viral molecular mimicry shows multiple host pulmonary–arterial peptides mimicked by SARS-CoV-2

open access: yesCell Death Discovery, 2020
The hand of molecular mimicry in shaping SARS-CoV-2 evolution and immune evasion remains to be deciphered. Here, we report 33 distinct 8-mer/9-mer peptides that are identical between SARS-CoV-2 and the human reference proteome.
A. Venkatakrishnan   +5 more
semanticscholar   +1 more source

Molecular mimicry: Basis for autoimmunity [PDF]

open access: yesIndian Journal of Clinical Biochemistry, 2000
Structural similarity between a viral protein and a self-component can trigger an autoimmune response, which is the basis of molecular mimicry. Alternatively an invading virus can induce an inflammatory response which in turn can initiate an attack by hitherto dormant T cells on a specific self-antigen, a phenomenon which is referred to as Bystander ...
openaire   +3 more sources

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