Results 241 to 250 of about 6,315,441 (313)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Gold Nanoparticle-Based Systems for Targeting the Ara h2 Allergen: A Molecular Modeling Approach. [PDF]

Comput Struct Biotechnol J
Mehranfar A, Shakya AK, Faller R.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Identification of natural TLR4 modulators through network pharmacology and molecular modeling in SARS-CoV-2 <i>Acinetobacter baumannii</i> co-infection. [PDF]

Front Chem
Ouassaf M, Khan SU, Rengasamy KRR, Alhaggass NS, Alhatlani BY.   +4 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Mechanistic insights into daidzin from Glycine max against breast cancer via network pharmacology and multi-level molecular modeling. [PDF]

PLoS One
Vu LT, Vu LT, Vu LTK, Pho HTT, Nguyen QH, Nguyen LTN, Nguyen YTH, Nguyen HD, Chu MH.   +8 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Integrative network pharmacology and molecular modeling approaches reveal the therapeutic potential of <i>Syzygium samarangense</i> phytocompounds against diabetes retinopathy. [PDF]

Front Bioinform
Kandhan A, Mathew B, Thirugnanasambandam S.   +2 more
europepmc   +1 more source

Experimental Study and Molecular Modeling of Antibody Interactions with Different Fluoroquinolones. [PDF]

Int J Mol Sci
Meteleshko YI, Khrenova MG, Byzova NA, Xing S, Lei H, Zherdev AV, Dzantiev BB, Hendrickson OD.   +7 more
europepmc   +1 more source

Molecular modeling of 7-propanamide benzoxaboroles as CPSF3 inhibitors through docking-based 3D-QSAR and molecular dynamics simulations. [PDF]

RSC Adv
Ji L, Liu Y, Xu G.
europepmc   +1 more source