Results 21 to 30 of about 6,315,441 (313)
Bat coronaviruses related to SARS-CoV-2: what about their 3CL proteases (MPro)?
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Despite a huge effort by the scientific community to determine the animal reservoir of SARS-CoV-2, which led to the identification of several SARS-CoV-2-related viruses both in bats and in pangolins, the origin of SARS-CoV-2 is still not clear. Recently,
Matteo Pavan +3 more
doaj +1 more source
Assessment of Molecular Modeling & Simulation [PDF]
, 2002 This report reviews the development and applications of molecular and materials modeling in Europe and Japan in comparison to those in the United States.
core +1 more source
Quasi-1D physics in metal-organic frameworks: MIL-47(V) from first principles
Beilstein Journal of Nanotechnology, 2014 The geometric and electronic structure of the MIL-47(V) metal-organic framework (MOF) is investigated by using ab initio density functional theory (DFT) calculations.
Danny E. P. Vanpoucke +4 more
doaj +1 more source
Translational stem cell therapy: vascularized skin grafts in skin repair and regeneration
Journal of Translational Medicine, 2021 The skin is made up of a plethora of cells arranged in multiple layers with complex and intricate vascular networks, creating a dynamic microenvironment of cells-to-matrix interactions.
Qian Hua Phua +2 more
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Biomedicines, 2022 Adenosine receptors have been a promising class of targets for the development of new therapies for several diseases. In recent years, a renewed interest in this field has risen, thanks to the implementation of a novel class of agonists that lack the ...
Giovanni Bolcato +4 more
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Molecular psychiatry of zebrafish [PDF]
, 2014 Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry.
Parker, M. O. +14 more
core +1 more source
Single-chain dimers from de novo immunoglobulins as robust scaffolds for multiple binding loops
Nature Communications, 2023 Antibody derivatives have sought to recapitulate the antigen binding properties of antibodies, but with improved biophysical attributes convenient for therapeutic, diagnostic and research applications.
Jorge Roel-Touris +2 more
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3D Human Organoids: The Next “Viral” Model for the Molecular Basis of Infectious Diseases
Biomedicines, 2022 The COVID-19 pandemic has driven the scientific community to adopt an efficient and reliable model that could keep up with the infectious disease arms race.
Shirley Pei Shan Chia +3 more
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Journal of Chemical Theory and Computation, 2015 Abstract Nanodiscs are discoloidal protein–lipid particles that self-assemble from a mixture of lipids and membrane scaffold proteins. They form a highly soluble membrane mimetic that closely resembles a native-like lipid environment, unlike micelles. Nanodiscs are widely used for experimental studies of membrane proteins.
Iwona, Siuda, D Peter, Tieleman
openaire +2 more sources
Nature Communications, 2018 Rational design of metal organic frameworks (MOFs) with shape-memory nanopores is a formidable challenge. Here the authors use an accurate theoretical approach to design thermo-responsive MOFs based on a balance of van der Waals and entropy contributions.
J. Wieme +3 more
doaj +1 more source