Results 71 to 80 of about 33,280,657 (326)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Inhibitory Effects of Bioactive Compounds of Tomato Juice Binding to Hepatic HMGCR: In Vivo Study and Molecular Modelling

PLoS ONE, 2014
The hypocholesterolemic effect of tomato juice has been investigated in an intervention study with rats, along with the possible inhibition effect of bioactive tomato compounds binding to the HMGCR enzyme.
I. Navarro-González, H. Pérez-Sánchez, G. Martín-Pozuelo, J. García-Alonso, M. Periago   +4 more
semanticscholar   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microalgae-Based Wastewater Treatment as a Circular Solution for Sustainable Resource Recovery [PDF]

BIO Web of Conferences
The need for sustainable and circular wastewater management solutions has increased due to water scarcity and environmental degradation. A promising eco-biotechnological strategy that can lower carbon emissions, recover valuable resources, and purify ...
Lamchaimech Aziza, El-Moustaqim Khadija, Abarkan Ahmed, Boudoudou Dalal, Boutarbouch Mounir, Ghailane Ayoub, Lamiri Chaimae, Ihouaten Abderrazzak, Mabrouki Jamal   +8 more
doaj   +1 more source

Molecular Modelling Study of the PPARγ Receptor in Relation to the Mode of Action/Adverse Outcome Pathway Framework for Liver Steatosis

International Journal of Molecular Sciences, 2014
The comprehensive understanding of the precise mode of action and/or adverse outcome pathway (MoA/AOP) of chemicals has become a key step toward the development of a new generation of predictive toxicology tools.
I. Tsakovska, M. Al Sharif, P. Alov, Antonia Diukendjieva, E. Fioravanzo, M. Cronin, I. Pajeva   +6 more
semanticscholar   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

A density functional theory insight into the structure and reactivity of diphenyltin(IV) derivative of glycylphenylalanine

Main Group Metal Chemistry, 2016
The quantum-chemical calculations based on density functional theory (DFT) have been performed on the diphenyltin(IV) derivative of glycyl-phenylalanine (H2L) at the B3LYP/6-31G(d,p)/LANL2DZ(Sn) level of theory without any symmetry constraint.
Pokharia Sandeep, Joshi Rachana, Pokharia Mamta, Yadav Swatantra Kumar, Mishra Hirdyesh   +4 more
doaj   +1 more source

Evaluating the purification efficiency of Moroccan waste stabilization ponds’ systems: challenges and future prospects [PDF]

The Holistic Approach to Environment
Lagoon wastewater treatment systems, introduced in 1970, have become a preferred economic solution in Morocco due to favourable climatic and economic conditions. However, these facilities often face performance problems, particularly related to excessive
Marouan Akdim, Latifa Tajounte, Abdelmajid Achkir, Mohammed El Mahi, Mokhtar Jaait, El Mostapha Lotfi   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source