Results 81 to 90 of about 33,280,657 (326)

Isomorphs in Model Molecular Liquids

The Journal of Physical Chemistry B, 2012
20 ...
Ingebrigtsen, Trond, Schrøder, Thomas, Dyre, J. C.; id_orcid 0000-0002-0770-5690   +2 more
openaire   +4 more sources

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Direct determination of amorphous number density from the reduced pair distribution function

MethodsX, 2019
The inference of amorphous bulk density, while straightforward for nonporous, soluble materials, may present a formidable challenge in some of the most important classes of industrial applications, involving melts, porous solids, and non-soluble organic ...
Georgios S.E. Antipas, Konstantinos T. Karalis   +1 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Molecular modelling study of the 3D structure of the biglycan core protein, using homology modelling techniques [PDF]

, 2013
Herein we report the establishment of the 3D structure of the biglycan core protein, using conventional homology molecular modelling techniques. The 3D model has been structurally optimised via molecular dynamics.
Feidakis, Christos, Champeris Tsaniras, Spyridon, Kossida, Sophia, Vlachakis, Dimitrios   +3 more
core   +8 more sources

Computational identification of phytochemical inhibitors targeting the AgrA quorum-sensing regulator of Staphylococcus aureus

In Silico Research in Biomedicine
Structure-based drug discovery offers an effective strategy for identifying anti-virulence agents against antibiotic-resistant pathogens. Staphylococcus aureus, particularly, considered as one of the most pathogenic organisms responsible for a broad set ...
Ajith Kumar K, Thulasi Sunilkumar, Aswathy R, Abhinav Hari, Niranjana Rajesh, Jaya Bisht, Varun T K, Arun Kumar Gangadharan, Dileep Francis   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Computational and Mathematical Modelling of the EGF Receptor System [PDF]

, 2008
This chapter gives an overview of computational and mathematical modelling of the EGF receptor system. It begins with a survey of motivations for producing such models, then describes the main approaches that are taken to carrying out such modelling, viz.
Emmet McIntyre, McIntyre, Emmet, Colin G. Johnson, William Gullick, Johnson, Colin G., Gullick, William J.   +5 more
core   +1 more source

A Theoretical Analysis of the Effects That the Glycocalyx and the Internal Elastic Lamina Have on Nitric Oxide Concentration Gradients in the Arterial Wall

Antioxidants
Nitric oxide (NO) is a well-known member of the reactive oxygen species (ROS) family. The extent of its concentration influences whether it produces beneficial physiological effects or harmful toxic reactions.
Yaroslav R. Nartsissov, Irena P. Seraya
doaj   +1 more source