Results 101 to 110 of about 319,211 (210)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Transducing chemical energy through catalysis by an artificial molecular motor. [PDF]

Nature
Wang PL, Borsley S, Power MJ, Cavasso A, Giuseppone N, Leigh DA.   +5 more
europepmc   +1 more source

3D printed protein-based robotic structures actuated by molecular motor assemblies. [PDF]

Nat Mater, 2022
Jia H, Flommersfeld J, Heymann M, Vogel SK, Franquelim HG, Brückner DB, Eto H, Broedersz CP, Schwille P.   +8 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Photoswitchable Molecular Motor Phospholipid: Synthesis, Characterization, and Integration into Lipid Vesicles. [PDF]

Langmuir
Guinart A, Doellerer D, Qutbuddin Y, Zivkovic H, Branca C, Hrebik D, Schwille P, Feringa BL.   +7 more
europepmc   +1 more source

On the functioning mechanism of an ATP-driven molecular motor. [PDF]

Biophys Physicobiol, 2021
Kinoshita M.
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Highly Efficient Near-Infrared Light-Driven Molecular Motor Rotation Enabled by Upconversion Nanoparticles as Nanoscale Light Sources. [PDF]

J Am Chem Soc
Sheng J, Fu Y, Wu K, Freese T, Zhang H, Feringa BL.   +5 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Structural Influence of the Chemical Fueling System on a Catalysis-Driven Rotary Molecular Motor. [PDF]

J Am Chem Soc
Liu HK, Mrad TW, Troncossi A, Borsley S, Roberts BMW, Betts A, Leigh DA.   +6 more
europepmc   +1 more source