Results 111 to 120 of about 358,120 (301)
Measuring molecular motor forces to probe transport regulation in vivo
, 2013 textThe cell relies on molecular motor proteins for long range transport of vesicles and organelles to maintain the organization required within the cell as it changes over time.
Leidel, Christina Paulette
core
Muscle wasting and weakness are critical clinical problems that limit mobility and independence, reduce health span, and increase the risk of physical disability. The molecular basis for this has not been fully determined.
Akanksha Agrawal +21 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Stokes Efficiency of Molecular Motor-Cargo Systems [PDF]
, 2008 and Applied Analysis, Vol. 2008, Article ID 241738, 2008The article of record as published may be found at http://dx.doi.org/10.1155/2008/241736A molecular motor utilizes chemical free energy to generate a unidirectional motion through the viscous fluid ...
Wang, Hongyun +3 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Introduction: Molecular Motors [PDF]
Chemical Reviews, 2020 Ryota Iino, Kazushi Kinbara, Zev Bryant
openaire +2 more sources
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Assembly of sensory-motor connectivity in the spinal cord of mice [PDF]
, 2007 Many features critical for proper functioning of an organism are under the control of neuronal circuits. The building blocks for these circuits are formed early during embryogenesis and are generated by the specification of distinct neuronal types.
Vrieseling, Eline
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Processivity of dimeric kinesin‐1 molecular motors
FEBS Open Bio, 2018 Kinesin‐1 is a homodimeric motor protein that can move along microtubule filaments by hydrolyzing ATP with a high processivity. How the two motor domains are coordinated to achieve such high processivity is not clear.
Si‐Kao Guo +3 more
doaj +1 more source