Results 101 to 110 of about 4,509,513 (302)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Detailed statement of motor vehicle registrations (in units)
, 2007 Annual; Description based on: 2000; title from caption (viewed Aug.
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Summary statement of motor vehicle registrations (in dollars)
, 2007 Annual; Description based on: 2000; title from caption (viewed Aug.
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Summary statement of motor vehicle registrations (in dollars)
, 2005 Annual; Description based on: 2000; title from caption (viewed Aug.
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Dissecting the dsDNA viral packaging machinery: structural evolution and potential for therapeutics
Journal of VirologySome double-stranded DNA viruses, such as herpesviruses and bacteriophages, utilize a powerful molecular motor to package DNA into their capsids to liquid-crystalline density.
Makayla N. Leroux, Carolyn M. Teschke
doaj +1 more source
New Journal of Physics, 2015 We present a model for a feedback-controlled ratchet consisting of a Brownian particle and a moving, finite barrier that is shifted by an external agent depending on the position of the particle.
R K Schmitt +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Detailed statement of motor vehicle registrations (in units)
, 2002 Annual; Description based on: 2000; title from caption (viewed Aug.
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