Results 1 to 10 of about 25,177 (273)
Double Duty: Mitotic Kinesins and Their Post-Mitotic Functions in Neurons
Cells, 2021 Neurons, regarded as post-mitotic cells, are characterized by their extensive dendritic and axonal arborization. This unique architecture imposes challenges to how to supply materials required at distal neuronal components.
Supriya Swarnkar +1 more
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Nature Reviews Cancer, 2012 Kinesins are a family of molecular motors that travel unidirectionally along microtubule tracks to fulfil their many roles in intracellular transport or cell division. Over the past few years kinesins that are involved in mitosis have emerged as potential targets for cancer drug development.
Oliver Rath +2 more
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Kinesins in Caenorhabditis elegans neuronal morphogenesis [PDF]
Open BiologyNeuronal morphogenesis is regulated by intracellular transport and cytoskeletal dynamics. Kinesin superfamily proteins (KIFs), or kinesins, function as molecular motors for intracellular transport and as regulators of the microtubule cytoskeleton, making
Shinsuke Niwa, Kyoko Chiba
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PLoS Biology, 2022 Kinesins are microtubule (MT)-based motors important in cell division, motility, polarity, and intracellular transport in many eukaryotes. However, they are poorly studied in the divergent eukaryotic pathogens Plasmodium spp., the causative agents of ...
Ravish Rashpa +2 more
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Highly Loaded Behavior of Kinesins Increases the Robustness of Transport Under High Resisting Loads
PLoS Computational Biology, 2015 Kinesins are nano-sized biological motors which walk by repeating a mechanochemical cycle. A single kinesin molecule is able to transport its cargo about 1 μm in the absence of external loads.
Woochul Nam, Bogdan I Epureanu
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The functions of kinesin and kinesin-related proteins in eukaryotes [PDF]
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
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Kinesin-14: the roots of reversal [PDF]
BMC Biology, 2010 Kinesin-14 motor proteins step towards microtubule minus ends, in the opposite direction to other kinesins. Work on the still-enigmatic kinesin-14 mechanism published in BMC Structural Biology shows that the carboxyl terminus of the motor head undergoes ...
Cross Robert A
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Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes
BMC Genomics, 2006 Background Kinesins, a superfamily of molecular motors, use microtubules as tracks and transport diverse cellular cargoes. All kinesins contain a highly conserved ~350 amino acid motor domain.
Reddy Anireddy SN +2 more
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Potential roles for Kinesins at the cortical division site
Frontiers in Plant Science, 2012 Spatial control of cytokinesis is critical for cell and plant morphology. The plane of cell division is established at G2/M transition and is initially demarcated at the cortex of the cell by the cytoskeletal preprophase band (PPB) and subsequently ...
Elisabeth eLipka, Sabine eMüller
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The mechanism of kinesin inhibition by kinesin-binding protein [PDF]
eLife, 2020 Subcellular compartmentalisation is necessary for eukaryotic cell function. Spatial and temporal regulation of kinesin activity is essential for building these local environments via control of intracellular cargo distribution.
Joseph Atherton +8 more
doaj +6 more sources