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Chromosome segregation during mitosis depends on the action of the mitotic spindle, a self-organizing, bipolar protein machine which uses microtubules (MTs) and their associated motors. Members of the BimC subfamily of kinesin-related MT-motor proteins are believed to be essential for the formation and functioning of a normal bipolar spindle.
Kashina, A. S +5 more
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Prime movers : mechanochemistry of mitotic kinesins [PDF]
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
Cross, R. A., McAinsh, Andrew D.
core +1 more source
Kinesins in the Arabidopsis genome: A comparative analysis among eukaryotes
Background Kinesins constitute a superfamily of microtubule motor proteins that are found in eukaryotic organisms. Members of the kinesin superfamily perform many diverse cellular functions such as transport of vesicles and organelles, spindle formation ...
Day Irene S, Reddy Anireddy SN
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During metaphase, chromosome position at the spindle equator is regulated by the forces exerted by kinetochore microtubules and polar ejection forces. However, the role of forces arising from mechanical coupling of sister kinetochore fibers with bridging
Mihaela Jagrić +4 more
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Absence of DEATH kinesin is fatal for Leishmania mexicana amastigotes
Kinesins are motor proteins present in organisms from protists to mammals playing important roles in cell division, intracellular organisation and flagellum formation and maintenance.
Suad Gazi Jaafer Husaine Al Kufi +5 more
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Multiple kinesins induce tension for smooth cargo transport
How cargoes move within a crowded cell—over long distances and at speeds nearly the same as when moving on unimpeded pathway—has long been mysterious.
Marco Tjioe +7 more
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Universal and unique features of kinesin motors: Insights from a comparison of fungal and animal conventional kinesins [PDF]
Kinesins are microtubule motors that use the energy derived from the hydrolysis of ATP to move unidirectionally along microtubules, The founding member of this still growing superfamily is conventional kinesin, a dimeric motor that moves processively ...
Woehlke, G. +5 more
core +1 more source
Summary: BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to
Raffaella De Pace +7 more
doaj +1 more source
Aspergillus niger is an important filamentous fungus in industrial biotechnology for the production of citric acid and enzymes. In the late 1980s, the A. niger N400/NRRL3 strain was selected for both fundamental and applied studies in relation to several
Ebru Demirci +8 more
doaj +1 more source
Kinesin as an Electrostatic Machine [PDF]
Kinesin and related motor proteins utilize ATP fuel to propel themselves along the external surface of microtubules in a processive and directional fashion. We show that the observed step-like motion is possible through time varying charge distributions furnished by the ATP hydrolysis circle while the static charge configuration on the microtuble ...
Alva, Aleix +2 more
openaire +4 more sources

