Results 21 to 30 of about 9,389 (207)
Kinesin as an Electrostatic Machine [PDF]
Journal of Biological Physics, 2006 Kinesin and related motor proteins utilize ATP fuel to propel themselves along the external surface of microtubules in a processive and directional fashion. We show that the observed step-like motion is possible through time varying charge distributions furnished by the ATP hydrolysis circle while the static charge configuration on the microtuble ...
Alva, Aleix +2 more
openaire +4 more sources
Multiple kinesins induce tension for smooth cargo transport
eLife, 2019 How cargoes move within a crowded cell—over long distances and at speeds nearly the same as when moving on unimpeded pathway—has long been mysterious.
Marco Tjioe +7 more
doaj +1 more source
Cell Reports, 2020 Summary: BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to
Raffaella De Pace +7 more
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The cooperative roles of two kinetoplastid-specific kinesins in cytokinesis and in maintaining cell morphology in bloodstream trypanosomes. [PDF]
PLoS ONE, 2013 The cytoskeleton of Trypanosoma brucei, a unicellular eukaryote and a parasitic protozoan, is defined by the subpellicular microtubule corset that is arranged underneath the plasma membrane. We recently identified two orphan kinesins, TbKIN-C and TbKIN-D,
Ying Wei +3 more
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Frontiers in Genetics, 2021 Aspergillus niger is an important filamentous fungus in industrial biotechnology for the production of citric acid and enzymes. In the late 1980s, the A. niger N400/NRRL3 strain was selected for both fundamental and applied studies in relation to several
Ebru Demirci +8 more
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Identification and phylogenetic analysis of
BMC Genomics, 2003 Background Kinesins constitute a large superfamily of motor proteins in eukaryotic cells. They perform diverse tasks such as vesicle and organelle transport and chromosomal segregation in a microtubule- and ATP-dependent manner.
Glöckner Gernot, Kollmar Martin
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Phosphoregulation of Kinesins Involved in Long-Range Intracellular Transport
Frontiers in Cell and Developmental Biology, 2022 Kinesins, the microtubule-dependent mechanochemical enzymes, power a variety of intracellular movements. Regulation of Kinesin activity and Kinesin-Cargo interactions determine the direction, timing and flux of various intracellular transports.
Diksha Kumari, Krishanu Ray
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Potential roles for Kinesins at the cortical division site
Frontiers in Plant Science, 2012 Spatial control of cytokinesis is critical for cell and plant morphology. The plane of cell division is established at G2/M transition and is initially demarcated at the cortex of the cell by the cytoskeletal preprophase band (PPB) and subsequently ...
Elisabeth eLipka, Sabine eMüller
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BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor
eLife, 2020 Low-density lipoprotein receptor (LDLR) in hepatocytes plays a key role in plasma clearance of circulating LDL and in whole body cholesterol homeostasis.
Chang Zhang +3 more
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Molecular Motor KIF3B Acts as a Key Regulator of Dendritic Architecture in Cortical Neurons
Frontiers in Cellular Neuroscience, 2020 Neurons require a well-coordinated intercellular transport system to maintain their normal cellular function and morphology. The kinesin family of proteins (KIFs) fills this role by regulating the transport of a diverse array of cargos in post-mitotic ...
Nadine F. Joseph +5 more
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