Molecular Network-Based Identification of Tramadol Metabolites in a Fatal Tramadol Poisoning
Metabolites, 2022 Identification of xenobiotics and their phase I/II metabolites in poisoned patients remains challenging. Systematic approaches using bioinformatic tools are needed to detect all compounds as exhaustively as possible.
Romain Magny +5 more
doaj +2 more sources
Genetic effects on molecular network states explain complex traits. [PDF]
Mol Syst Biol, 2023 The complexity of many cellular and organismal traits results from the integration of genetic and environmental factors via molecular networks. Network structure and effect propagation are best understood at the level of functional modules, but so far ...
Weith M +10 more
europepmc +2 more sources
Molecular networks in Network Medicine: Development and applications [PDF]
WIREs Systems Biology and Medicine, 2020 Network Medicine applies network science approaches to investigate disease pathogenesis. Many different analytical methods have been used to infer relevant molecular networks, including protein–protein interaction networks, correlation‐based networks ...
E. Silverman +25 more
semanticscholar +11 more sources
Molecular ecological network analyses [PDF]
BMC Bioinformatics, 2012 BackgroundUnderstanding the interaction among different species within a community and their responses to environmental changes is a central goal in ecology.
Ye Deng +5 more
semanticscholar +5 more sources
Epidemiological characteristics of HIV transmission in southeastern China from 2015 to 2020 based on HIV molecular network [PDF]
Frontiers in Public Health, 2023 ObjectiveHIV/AIDS remains a global public health problem, and understanding the structure of social networks of people living with HIV/AIDS is of great importance to unravel HIV transmission, propose precision control and reduce new infections.
Zhenghua Wang +14 more
doaj +2 more sources
Molecular network analysis for detecting HIV transmission clusters: insights and implications [PDF]
Frontiers in Public HealthObjectiveIn order to improve knowledge of HIV transmission dynamics and guide preventive and control strategies, this work uses molecular cluster analysis to objectively detect clusters of HIV genetic sequence similarity.Methods89 HIV-positive couples ...
Yangyang Liu +5 more
doaj +2 more sources
Design of a directed molecular network [PDF]
Proceedings of the National Academy of Sciences, 2004 An ability to rationally design complex networks from the bottom up can offer valuable quantitative model systems for use in gaining a deeper appreciation for the principles governing the self-organization and functional characteristics of complex systems.
Gonen Ashkenasy +3 more
openalex +4 more sources
Molecular Network Basis of Invasive Pituitary Adenoma: A Review
Frontiers in Endocrinology, 2019 Cases with pituitary adenoma comprise 10–25% of intracranial neoplasm, being the third most common intracranial tumor, most of the adenomas are considered to be benign. About 35% of pituitary adenomas are invasive.
Qi Yang, Xuejun Li
doaj +2 more sources
Molecular network characteristics and drug resistance analysis of 392 newly reported MSM HIV/AIDS cases in Chongqing, China [PDF]
Frontiers in Public HealthTo comprehensively investigate the molecular transmission patterns of HIV-1 genotypes among men who have sex with men (MSM) in Chongqing, we employed 392 pol sequences of MSM to construct a phylogenetic tree and gene transmission network. Among the viral
Chongyang Bai +7 more
doaj +2 more sources
Molecular Network of Colorectal Cancer and Current Therapeutic Options
Frontiers in Oncology, 2022 Colorectal cancer (CRC), a leading cause of cancer-related mortalities globally, results from the accumulation of multiple genetic and epigenetic alterations in the normal colonic and rectum epithelium, leading to the progression from colorectal adenomas
Zhe Huang, Mingli Yang
semanticscholar +1 more source