Results 31 to 40 of about 33,672 (217)

Molecular Network Analysis Reveals Transmission of HIV-1 Drug-Resistant Strains Among Newly Diagnosed HIV-1 Infections in a Moderately HIV Endemic City in China

Frontiers in Microbiology, 2022
Since the implementation of the “treat all” policy in China in 2016, there have been few data on the prevalence of transmitted drug resistance (TDR) in China.
Bin Zhao, Bin Zhao, Bin Zhao, Bin Zhao, Wei Song, Mingming Kang, Mingming Kang, Mingming Kang, Xue Dong, Xin Li, Lu Wang, Jianmin Liu, Haibo Ding, Haibo Ding, Haibo Ding, Haibo Ding, Zhenxing Chu, Zhenxing Chu, Zhenxing Chu, Zhenxing Chu, Lin Wang, Lin Wang, Lin Wang, Lin Wang, Yu Qiu, Yu Qiu, Yu Qiu, Yu Qiu, Hong Shang, Hong Shang, Hong Shang, Hong Shang, Xiaoxu Han, Xiaoxu Han, Xiaoxu Han, Xiaoxu Han   +35 more
doaj   +1 more source

Feature-Based Molecular Network-Guided Dereplication of Natural Bioactive Products from Leaves of Stryphnodendron pulcherrimum (Willd.) Hochr

Metabolites, 2021
Stryphnodendron pulcherrimum is a species known to have a high content of tannins. Accordingly, its preparations are used in southern Pará, Brazil, for their anti-inflammatory and antimicrobial activities, but so far, its chemical profile composition ...
Paulo Gomes, Luis Quirós-Guerrero, Consuelo Silva, Sônia Pamplona, Jean A. Boutin, Marcos Eberlin, Jean-Luc Wolfender, Milton Silva   +7 more
doaj   +1 more source

Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma

Frontiers in Oncology, 2021
RNA-binding motif protein 8A (RBM8A) is abnormally overexpressed in hepatocellular carcinoma (HCC) and involved in the epithelial-mesenchymal transition (EMT).
Rong Liang, Jinyan Zhang, Zhihui Liu, Ziyu Liu, Qian Li, Xiaoling Luo, Yongqiang Li, Jiazhou Ye, Yan Lin   +8 more
doaj   +1 more source

Construction of a Molecular Learning Network

Journal of Advanced Computational Intelligence and Intelligent Informatics, 2013
Learning ability in unicellular organisms has been studied since the first half of the 20th century, but there is still no clear evidence of unicellular learning. Based on results from previous associative learning experiments using thePhysarumplasmodium, a gene regulatory network model of unicellular learning was constructed.
Tomohiro Shirakawa, Hiroshi Sato
openaire   +1 more source

Uncovering the molecular networks in periodontitis [PDF]

PROTEOMICS – Clinical Applications, 2014
Periodontitis is a complex immune‐inflammatory disease that results from a preestablished infection in gingiva, mainly due to Gram‐negative bacteria that colonize deeper in gingival sulcus and latter periodontal pocket. Host inflammatory and immune responses have both protective and destructive roles.
Fábio, Trindade, Frank G, Oppenheim, Eva J, Helmerhorst, Francisco, Amado, Pedro S, Gomes, Rui, Vitorino   +5 more
openaire   +2 more sources

Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort

Acta Neuropathologica Communications
This study aims to elucidate the clinical and molecular characteristics, treatment outcomes and prognostic factors of patients with histone H3 K27-mutant diffuse midline glioma.
Nobuhide Hayashi, Junya Fukai, Hirokazu Nakatogawa, Hiroshi Kawaji, Ema Yoshioka, Yoshinori Kodama, Kosuke Nakajo, Takehiro Uda, Kentaro Naito, Noriyuki Kijima, Yoshiko Okita, Naoki Kagawa, Yoshinobu Takahashi, Naoya Hashimoto, Hideyuki Arita, Koji Takano, Daisuke Sakamoto, Tomoko Iida, Yoshiki Arakawa, Takeshi Kawauchi, Yukihiko Sonoda, Yuta Mitobe, Kenichi Ishibashi, Masahide Matsuda, Takamune Achiha, Takahiro Tomita, Masahiro Nonaka, Keijiro Hara, Noriyoshi Takebe, Takashi Tsuzuki, Yoshikazu Nakajima, Shiro Ohue, Nobuyuki Nakajima, Akira Watanabe, Akihiro Inoue, Masao Umegaki, Daisuke Kanematsu, Asako Katsuma, Miho Sumida, Tomoko Shofuda, Masayuki Mano, Manabu Kinoshita, Kanji Mori, Naoyuki Nakao, Yonehiro Kanemura   +44 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Molecular hypergraph neural networks

The Journal of Chemical Physics
Graph neural networks (GNNs) have demonstrated promising performance across various chemistry-related tasks. However, conventional graphs only model the pairwise connectivity in molecules, failing to adequately represent higher order connections, such as multi-center bonds and conjugated structures.
Junwu Chen, Philippe Schwaller
openaire   +3 more sources

The Molecular Design Research Network [PDF]

Toxicological Sciences, 2017
Herein, we provide an overview of a research network that is aimed at fostering interdisciplinary collaboration between chemists and toxicologists with the goal of rationally designing safer commercial chemicals. The collaborative is the Molecular Design Research Network (MoDRN) that was created in 2013 with funding from the EPA-National Science ...
Philip, Coish, Bryan W, Brooks, Evan P, Gallagher, Margaret, Mills, Terrance J, Kavanagh, Nancy, Simcox, Grace A, Lasker, Dianne, Botta, Stephanie C, Schmuck, Adelina, Voutchkova-Kostal, Jakub, Kostal, Melissa L, Mullins, Suzanne M, Nesmith, Karolina E, Mellor, Jone, Corrales, Lauren A, Kristofco, Gavin N, Saari, Baylor, Steele, Longzhu Q, Shen, Fjodor, Melnikov, Julie B, Zimmerman, Paul T, Anastas   +21 more
openaire   +2 more sources

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source