Results 21 to 30 of about 2,051,496 (327)

Chemical Proportionality within Molecular Networks [PDF]

open access: yesAnalytical Chemistry, 2021
Molecular networking of non-targeted tandem mass spectrometry data connects structurally related molecules based on similar fragmentation spectra. Here we report the Chemical Proportionality contextualization of molecular networks. ChemProp scores the changes of abundance between two connected nodes over sequential data series which can be displayed as
Daniel Petras   +10 more
openaire   +2 more sources

Epidemiology and Molecular Transmission Characteristics of HIV in the Capital City of Anhui Province in China

open access: yesPathogens, 2021
Hefei, Anhui province, is one of the cities in the Yangtze River Delta, where many people migrate to Jiangsu, Zhejiang and Shanghai. High migration also contributes to the HIV epidemic.
Shan Zheng   +12 more
doaj   +1 more source

Lipidomics of Environmental Microbial Communities. II: Characterization Using Molecular Networking and Information Theory

open access: yesFrontiers in Microbiology, 2021
Structurally diverse, specialized lipids are crucial components of microbial membranes and other organelles and play essential roles in ecological functioning. The detection of such lipids in the environment can reveal not only the occurrence of specific
Su Ding   +9 more
doaj   +1 more source

Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

open access: yesActa Neuropathologica Communications, 2019
The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact
Toru Umehara   +20 more
doaj   +1 more source

Integration of molecular network data reconstructs Gene Ontology. [PDF]

open access: yes, 2014
Motivation: Recently, a shift was made from using Gene Ontology (GO) to evaluate molecular network data to using these data to construct and evaluate GO. Dutkowski et al. provide the first evidence that a large part of GO can be reconstructed solely from
Gligorijević, V, Janjić, V, Pržulj, N
core   +2 more sources

The Hippo Signaling Pathway: The Trader of Tumor Microenvironment

open access: yesFrontiers in Oncology, 2021
The Hippo pathway regulates cancer biology in many aspects and the crosstalk with other pathways complicates its role. Accumulated evidence has shown that the bidirectional interactions between tumor cells and tumor microenvironment (TME) are the ...
Duo Yang   +5 more
doaj   +1 more source

One Hub-One Process: A Tool Based View on Regulatory Network Topology [PDF]

open access: yes, 2007
The relationship between the regulatory design and the functionality of molecular networks is a key issue in biology. Modules and motifs have been associated to various cellular processes, thereby providing anecdotal evidence for performance based ...
Axelsen, Jacob Bock   +2 more
core   +4 more sources

Graph Embedding Based Novel Gene Discovery Associated With Diabetes Mellitus

open access: yesFrontiers in Genetics, 2021
Diabetes mellitus is a group of complex metabolic disorders which has affected hundreds of millions of patients world-widely. The underlying pathogenesis of various types of diabetes is still unclear, which hinders the way of developing more efficient ...
Jianzong Du   +6 more
doaj   +1 more source

Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]

open access: yes, 2006
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C.   +3 more
core   +4 more sources

Myosin II filament dynamics in actin networks revealed with interferometric scattering microscopy [PDF]

open access: yes, 2020
The plasma membrane and the underlying cytoskeletal cortex constitute active platforms for a variety of cellular processes. Recent work has shown that the remodeling acto-myosin network modifies local membrane organization, but the molecular details are ...
Fineberg, A.   +7 more
core   +1 more source

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