Results 31 to 40 of about 11,611,859 (368)
Molecular network-based intervention brings us closer to ending the HIV pandemic
Frontiers in Medicine, 2020 Precise identification of HIV transmission among populations is a key step in public health responses. However, the HIV transmission network is usually difficult to determine.
Xiaoxu Han +4 more
semanticscholar +1 more source
Unifying the essential concepts of biological networks: biological insights and philosophical foundations [PDF]
, 2020 Over the last decades, network-based approaches have become highly popular in diverse fields of biology, including neuroscience, ecology, molecular biology and genetics.
Hilgetag, Claus +2 more
core +2 more sources
Acta Neuropathologica Communications, 2019 The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact
Toru Umehara +20 more
doaj +1 more source
The Hippo Signaling Pathway: The Trader of Tumor Microenvironment
Frontiers in Oncology, 2021 The Hippo pathway regulates cancer biology in many aspects and the crosstalk with other pathways complicates its role. Accumulated evidence has shown that the bidirectional interactions between tumor cells and tumor microenvironment (TME) are the ...
Duo Yang +5 more
doaj +1 more source
SARS-CoV-2 Molecular Network Structure
Frontiers in Physiology, 2020 Knowledge about the molecular basis of SARS-CoV-2 infection is incipient. However, recent experimental results about the virus interactome have shown that this single-positive stranded RNA virus produces a set of about 28 specific proteins grouped into ...
José Díaz
semanticscholar +1 more source
Molecular Networking as a Dereplication Strategy [PDF]
Journal of Natural Products, 2013 A major goal in natural product discovery programs is to rapidly dereplicate known entities from complex biological extracts. We demonstrate here that molecular networking, an approach that organizes MS/MS data based on chemical similarity, is a powerful complement to traditional dereplication strategies.
William H. Gerwick +16 more
openaire +5 more sources
Graph Embedding Based Novel Gene Discovery Associated With Diabetes Mellitus
Frontiers in Genetics, 2021 Diabetes mellitus is a group of complex metabolic disorders which has affected hundreds of millions of patients world-widely. The underlying pathogenesis of various types of diabetes is still unclear, which hinders the way of developing more efficient ...
Jianzong Du +6 more
doaj +1 more source
Molecular Network Profiling in Intestinal- and Diffuse-Type Gastric Cancer
Cancers, 2020 Simple Summary Cancer has several phenotypic subtypes where the responsiveness towards drugs or capacity of migration or recurrence are different. The molecular networks are dynamically altered in various phenotypes of cancer.
Shihori Tanabe +7 more
semanticscholar +1 more source
Nature Neuroscience, 2018 There is a need for new therapeutic targets with which to prevent Alzheimer’s disease (AD), a major contributor to aging-related cognitive decline. Here we report the construction and validation of a molecular network of the aging human frontal cortex ...
S. Mostafavi +20 more
semanticscholar +1 more source
One Hub-One Process: A Tool Based View on Regulatory Network Topology [PDF]
, 2007 The relationship between the regulatory design and the functionality of molecular networks is a key issue in biology. Modules and motifs have been associated to various cellular processes, thereby providing anecdotal evidence for performance based ...
Axelsen, Jacob Bock +2 more
core +4 more sources