Results 11 to 20 of about 93,666 (291)

Molecular signatures of attention networks

Human Brain Mapping, 2023
Abstract Attention network theory proposes three distinct types of attention—alerting, orienting, and control—that are supported by separate brain networks and modulated by different neurotransmitters, that is, norepinephrine, acetylcholine, and dopamine.
Hanna Schindler, Philippe Jawinski, Aurina Arnatkevičiūtė, Sebastian Markett   +3 more
openaire   +2 more sources

A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]

, 2010
Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex, Altschul, Anja Joachim, Ashburner, Bentley, Bethony, Björnberg, Blaxter, Boag, Bronwyn E. Campbell, Caffrey, Campbell, Cantacessi, Cantacessi, Cantacessi, Cantacessi, Chan, Chang, Cinzia Cantacessi, Clifton, Conesa, Cottee, Cottee, Datu, DeRisi, Doyle, Flicek, Freigofas, Gasser, Golden, Greene, Gupta, Hawdon, Hopkins, Hotez, Hu, Huang, Hunter, Iseli, Jackson, Joachim, Joachim, Keil, Krasky, Letunic, Li, Li, Li, Lipinski, Makedonka Mitreva, Margulies, Matthew J. Nolan, McKay, Metzker, Miller, Miller, Mizuarai, Moreno, Morozova, Moser, Mufson, Mulvenna, Nagaraj, Nagaraj, Neil D. Young, Nikolaou, Nisbet, Olson, Parkinson, Paul W. Sternberg, Pong, Portman, Ranganathan, Ren, Robertson, Robin B. Gasser, Robinson, Ross S. Hall, Sahar Abubucker, Sanger, Sanger, Santos, Shoba Ranganathan, Soderlund, Stathopoulos, Stockdale, Tanaka, Vibranovski, Wang, Williamson, Wilson, Wu, Young, Young, Zhan, Zhong   +95 more
core   +6 more sources

REDES MOLECULARES: UMA ANÁLISE SOBRE ANOTAÇÕES E DESCOBERTA DE NOVOS ATIVOS

Química Nova, 2021
MOLECULAR NETWORKS: AN ANALYSIS ON ANNOTATIONS AND DISCOVERY OF NEW ASSETS. To speed up the discovery of bioactive natural products (NP), chemists have sought advanced approaches in analytical and computational chemistry in attempt to organize and ...
Alan C Pilon, Natália C Vieira, Juliano G Amaral, Afif F Monteiro, Ricardo R. da Silva, Laila S Spíndola, Ian Castro-Gamboa, Norberto P Lopes   +7 more
doaj   +1 more source

Chemical Proportionality within Molecular Networks [PDF]

Analytical Chemistry, 2021
Molecular networking of non-targeted tandem mass spectrometry data connects structurally related molecules based on similar fragmentation spectra. Here we report the Chemical Proportionality contextualization of molecular networks. ChemProp scores the changes of abundance between two connected nodes over sequential data series which can be displayed as
Daniel Petras, Andrés Mauricio Caraballo-Rodríguez, Alan K. Jarmusch, Carlos Molina-Santiago, Julia M. Gauglitz, Emily C. Gentry, Pedro Belda-Ferre, Diego Romero, Shirley M. Tsunoda, Pieter C. Dorrestein, Mingxun Wang   +10 more
openaire   +2 more sources

Methods in Microbial Biodiscovery

Marine Drugs, 2021
This review presents an account of the microbial biodiscovery methodology developed and applied in our laboratory at The University of Queensland, Institute for Molecular Bioscience, with examples drawn from our experiences studying natural products ...
Angela A. Salim, Zeinab G. Khalil, Ahmed H. Elbanna, Taizong Wu, Robert J. Capon   +4 more
doaj   +1 more source

Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders

Frontiers in Behavioral Neuroscience, 2014
DISC1 (disrupted in schizophrenia-1) gene is associated with several neuropsychiatric disorders as it is disrupted by a balanced translocation involving chromosomes 1 and 11 in a large Scottish pedigree with high prevalence of schizophrenia, bipolar ...
Raquel eGomez-Sintes, Raquel eGomez-Sintes, Mirna eKvajo, Joseph A Gogos, Jose J Lucas, Jose J Lucas   +5 more
doaj   +1 more source

Feature-Based Molecular Networking for the Exploration of the Metabolome Diversity of Common Egyptian Centaurea Species in Relation to Their Cytotoxic Activity

Molecules, 2023
Centaurea is a genus compromising over 250 herbaceous flowering species and is used traditionally to treat several ailments. Among the Egyptian Centaurea species, C. lipii was reported to be cytotoxic against multidrug-resistant cancer cells.
Eman H. Reda, Nesrine M. Hegazi, Mona Marzouk, Zienab T. Abdel Shakour, Ali M. El-Halawany, El-Sayeda A. El-Kashoury, Tarik A. Mohamed, Mahmoud A. A. Ibrahim, Khaled A. Shams, Nahla S. Abdel-Azim, Christopher J. Kampf, Thomas Efferth, Paul. W. Paré, Mohamed-Elamir F. Hegazy   +13 more
doaj   +1 more source

Using molecular networking for microbial secondary metabolite bioprospecting [PDF]

, 2016
The oceans represent an understudied resource for the isolation of bacteria with the potential to produce novel secondary metabolites. In particular, actinomyces are well known to produce chemically diverse metabolites with a wide range of biological ...
Brennan, Debra, Duncan, Katherine, Edrada-Ebel, Ruangelie, Green, David H., Hreggviðsson, Guðmundur Ó., Kuttner, Eva, Macintyre, Lynsey, Purves, Kevin, Young, Louise C., Ásgeirsdóttir, Margrét E.   +9 more
core   +2 more sources

New Sorbicillinoids from the Mangrove Endophytic Fungus Trichoderma reesei SCNU-F0042

Marine Drugs, 2023
Three new dimeric sorbicillinoids (1–3) and one new 3,4,6-trisubstituted α-pyrone (5), along with seven analogues (4 and 6–11), were isolated from the mangrove endophytic fungus Trichoderma reesei SCNU-F0042 under the guidance of molecular networking ...
Jialin Li, Tao Chen, Jianchen Yu, Hao Jia, Chen Chen, Yuhua Long   +5 more
doaj   +1 more source

An Integrated Molecular Networking and Docking Approach to Characterize the Metabolome of Helichrysum splendidum and Its Pharmaceutical Potentials

Metabolites, 2023
South Africa is rich in diverse medicinal plants, and it is reported to have over 35% of the global Helichrysum species, many of which are utilized in traditional medicine.
Motseoa Mariam Lephatsi, Mpho Susan Choene, Abidemi Paul Kappo, Ntakadzeni Edwin Madala, Fidele Tugizimana   +4 more
doaj   +1 more source