Results 51 to 60 of about 93,666 (291)

Comparison of established and emerging biodosimetry assays [PDF]

, 2013
Rapid biodosimetry tools are required to assist with triage in the case of a large-scale radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well-established dicentric chromosome assay (DCA) and cytokinesis-block ...
Abend, M, Badie, C, Balagurunathan, Y, Barnard, S, Beinke, C, Bernard, N, Boulay-Greene, H, Braselmann, H, Brengues, M, De Amicis, A, De Sanctis, S, Greither, R, Herodin, F, Jones, A, Kabacik, S, Knie, T, Kulka, U, Lista, F, Martigne, P, Meineke, V, Missel, A, Moquet, J, Oestreicher, U, Peinnequin, A, Poyot, T, Roessler, U, Romm, H, Rothkamm, K, Scherthan, H, Terbrueggen, B, Thierens, Hubert, Valente, M, Vral, Anne, Zenhausern, F   +33 more
core   +2 more sources

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Enhanced Molecular Networking Shows Microbacterium sp. V1 as a Factory of Antioxidant Proline-Rich Peptides

Marine Drugs, 2023
Two linear proline-rich peptides (1–2), bearing an N-terminal pyroglutamate, were isolated from the marine bacterium Microbacterium sp. V1, associated with the marine sponge Petrosia ficiformis, collected in the volcanic CO2 vents in Ischia Island (South
Giovanni Andrea Vitale, Silvia Scarpato, Alfonso Mangoni, Maria Valeria D’Auria, Gerardo Della Sala, Donatella de Pascale   +5 more
doaj   +1 more source

Initial Development toward Non-Invasive Drug Monitoring via Untargeted Mass Spectrometric Analysis of Human Skin. [PDF]

, 2019
Drug monitoring is crucial for providing accurate and effective care; however, current methods (e.g., blood draws) are inconvenient and unpleasant. We aim to develop a non-invasive method for the detection and monitoring of drugs via human skin.
Bouslimani, Amina, da Silva, Ricardo R, Del Rosario, Krizia K, Dorrestein, Pieter C, Elijah, Emmanuel O, Ernst, Madeleine, Jarmusch, Alan K, Tsunoda, Shirley M, Vargas, Fernando, Wang, Mingxun   +9 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Integrated Metabolomic, Molecular Networking, and Genome Mining Analyses Uncover Novel Angucyclines From Streptomyces sp. RO-S4 Strain Isolated From Bejaia Bay, Algeria

Frontiers in Microbiology, 2022
Multi-omic approaches have recently made big strides toward the effective exploration of microorganisms, accelerating the discovery of new bioactive compounds. We combined metabolomic, molecular networking, and genomic-based approaches to investigate the
Rima Ouchene, Rima Ouchene, Didier Stien, Juliette Segret, Mouloud Kecha, Alice M. S. Rodrigues, Carole Veckerlé, Marcelino T. Suzuki   +7 more
doaj   +1 more source

Modularity of Biochemical Filtering for Inducing Sigmoid Response in Both Inputs in an Enzymatic AND Gate

, 2013
We report the first systematic study of designed two-input biochemical systems as information processing gates with favorable noise-transmission properties accomplished by modifying the gate's response from convex shape to sigmoid in both inputs. This is
Bakshi, Saira, Halamek, Jan, Katz, Evgeny, Privman, Vladimir, Zavalov, Oleksandr   +4 more
core   +1 more source

Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. [PDF]

, 2017
Natural product screening programs have uncovered molecules from diverse natural sources with various biological activities and unique structures. However, much is yet underexplored and additional information is hidden in these exceptional collections ...
Ackermann, Gail, Alexandrov, Theodore, Amir, Amnon, Bandeira, Nuno, Dorrestein, Pieter C, Duggan, Brendan M, Garg, Neha, Gerwick, Lena, Gerwick, William H, Glukhov, Evgenia, Knight, Rob, Luzzatto-Knaan, Tal, Peng, Yao, Ryazanov, Sergey, Wang, Mingxun   +14 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Brain-derived extracellular vesicle proteomics reveals neuroprotection induced by the ARB candesartan in Parkinson’s disease patients

npj Parkinson's Disease
In models of Parkinson’s disease (PD), angiotensin-II type-1 receptor (AT1) blockers (ARBs) mitigated the vulnerability of dopaminergic neurons, which aligns with recent transcriptomic studies of human brains showing increased susceptibility of ...
Laura Camacho-Meño, Carmen M. Labandeira, Susana B. Bravo, Mateo V. Torres, Helena Bejr-Kasem, Angela Molina-Crespo, Mercedes Atienza, Jose L. Lanciego, Jose L. Cantero, Jaime Kulisevsky, Jose Luis Labandeira-Garcia, Ana I. Rodriguez-Perez   +11 more
doaj   +1 more source