Results 21 to 30 of about 909,959 (264)

Occurrence of Human Defensins and S100 Proteins in Head and Neck Basal Cell Carcinoma (BCC) Entities: hBD3 and S100A4 as Potential Biomarkers to Evaluate Successful Surgical Therapy

Journal of Otorhinolaryngology, Hearing and Balance Medicine, 2023
Background: The goal of this study is the identification of potential marker molecules for characterizing different basal cell carcinoma entities, to help improve clinical decisions for surgical resection therapy.
Eva Dröge, Rainer Probstmeier, Matthias Wenghoefer, Jochen Winter   +3 more
doaj   +1 more source

Current opinion: where are we in our understanding and treatment of osteoarthritis?

Swiss Medical Weekly, 2016
There has been important recent progress in our understanding of the molecular pathology of osteoarthritis (OA) and how it might be treated. New technologies have been developed and others refined to identify patients for recruitment in clinical trials
Anthony Robin Poole
doaj   +1 more source

The molecular pathology of noroviruses [PDF]

The Journal of Pathology, 2014
AbstractNorovirus infection in humans typically results in acute gastroenteritis but may also occur in many animal species. Noroviruses are recognized as one of the most common causes of acute gastroenteritis in the world, being responsible for almost 20% of all cases.
Stephanie M, Karst, Shu, Zhu, Ian G, Goodfellow   +2 more
openaire   +2 more sources

The paraffin-embedded RNA metric (PERM) for RNA isolated from formalin-fixed, paraffin-embedded tissue

BioTechniques, 2016
RNA isolated from formalin-fixed, paraffin-embedded (FFPE) tissue is commonly evaluated in both investigative and diagnostic pathology. However, the quality of the data is directly impacted by RNA quality.
Joon-Yong Chung, Hanbyoul Cho, Stephen M. Hewitt   +2 more
doaj   +1 more source

Research Progress of Diagnosis and Treatment of Glioblastoma

Zhongliu Fangzhi Yanjiu, 2022
Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
doaj   +1 more source

Update on pathology of ocular parasitic disease

Indian Journal of Ophthalmology, 2016
Parasites are a group of eukaryotic organisms that may be free-living or form a symbiotic or parasitic relationship with the hosts. Consisting of over 800,000 recognized species, parasites may be unicellular (Protozoa) or multicellular (helminths and ...
Dipankar Das, Varsha Ramachandra, Saidul Islam, Harsha Bhattacharjee, Jyotirmay Biswas, Akanksha Koul, Panna Deka, Apurba Deka   +7 more
doaj   +1 more source

Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma

Cancer Medicine, 2021
Background RNA‐sequencing‐based classifiers can stratify pancreatic ductal adenocarcinoma (PDAC) into prognostically significant subgroups but are not practical for use in clinical workflows.
Julia R. Naso, James T. Topham, Joanna M. Karasinska, Michael K.C. Lee, Steve E. Kalloger, Hui‐li Wong, Jessica Nelson, Richard A. Moore, Andrew J. Mungall, Steven J.M. Jones, Janessa Laskin, Marco A. Marra, Daniel J. Renouf, David F. Schaeffer   +13 more
doaj   +1 more source

Consensus Recommendations to Optimize the Detection and Reporting of NTRK Gene Fusions by RNA-Based Next-Generation Sequencing

Current Oncology, 2023
The detection of gene fusions by RNA-based next-generation sequencing (NGS) is an emerging method in clinical genetic laboratories for oncology biomarker testing to direct targeted therapy selections.
Tracy L. Stockley, Bryan Lo, Adrian Box, Andrea Gomez Corredor, John DeCoteau, Patrice Desmeules, Harriet Feilotter, Daria Grafodatskaya, Cynthia Hawkins, Weei Yuarn Huang, Iyare Izevbaye, Guylaine Lepine, Andreas I. Papadakis, Paul C. Park, Brandon S. Sheffield, Danh Tran-Thanh, Stephen Yip, Ming Sound Tsao   +17 more
doaj   +1 more source

Houston Methodist variant viewer: An application to support clinical laboratory interpretation of next-generation sequencing data for cancer

Journal of Pathology Informatics, 2017
Introduction: Next-generation-sequencing (NGS) is increasingly used in clinical and research protocols for patients with cancer. NGS assays are routinely used in clinical laboratories to detect mutations bearing on cancer diagnosis, prognosis and ...
Paul A Christensen, Yunyun Ni, Feifei Bao, Heather L Hendrickson, Michael Greenwood, Jessica S Thomas, S Wesley Long, Randall J Olsen   +7 more
doaj   +1 more source

The International System for Reporting Serous Fluid Cytopathology: How to Incorporate Molecular Data in Cytopathology Reports

Journal of Molecular Pathology, 2021
Serous effusion cytology is widely employed in the initial evaluation of the etiology of effusions with a high diagnostic sensitivity. To standardize practices, The International System for Reporting Serous Fluid Cytology (TIS) was developed following ...
Daniel Pinto, Ashish Chandra, Fernando Schmitt   +2 more
doaj   +1 more source