Results 131 to 140 of about 363,849 (261)

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Molecular pharmacology of receptors. IV

, 1991
http://tartu.ester.ee/record=b1078155~S1 ...
openaire   +2 more sources

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Methylcobalamin as a candidate for chronic peripheral neuropathic pain therapy: review of molecular pharmacology actiona. [PDF]

Korean J Pain
Ramadhani A, Astuti I, Widiastuti MG, Purwanti N.   +3 more
europepmc   +1 more source

Molecular pharmacology of ciclesonide against SARS-CoV-2. [PDF]

J Allergy Clin Immunol, 2020
Kimura H, Kurusu H, Sada M, Kurai D, Murakami K, Kamitani W, Tomita H, Katayama K, Ryo A.   +8 more
europepmc   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Editorial: Experimental and computational aspects of bioactive proteins from animal venoms: an insight into pharmacological properties and drug discovery

Frontiers in Pharmacology
Michelle Khai Khun Yap, Cassandra M. Modahl, Steven R. Hall   +2 more
doaj   +1 more source

Molecular Pharmacology of Glucagon-Like Peptide 1-Based Therapies in the Management of Type Two Diabetes Mellitus and Obesity. [PDF]

Integr Pharm Res Pract
Alzahrani AM, Alshobragi GA, Alshehri AM, Alzahrani MS, Alshehri HA, Alzhrani RM, Basudan S, Alkatheeri AA, Almutairi SA, Alzahrani YA.   +9 more
europepmc   +1 more source

Reprogramming Tumor Cell Death via Processing Natural Drug to Carbon Dots Overcomes Collagen Barrier and Activates Antitumor Immunity

Advanced Functional Materials, EarlyView.
A traditional Chinese medicine‐derived carbon dots nanoplatform reprograms tumor cell death from apoptosis to necroptosis, dismantling therapy‐induced collagen barriers and promoting immunogenic death. pH‐responsive hydrogel assembled from carbon dots for localized delivery, this strategy suppresses primary tumors and metastasis, offering a new ...
Zekun Yan, Hongwei Cheng, Yupeng Liu, Wenfeng Xu, Quansheng Cheng, Lingyun Li, Xue Wu, Yingqi Liang, Jing Zhao, Gang Liu, Shaoping Li, Songnan Qu   +11 more
wiley   +1 more source

Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors. [PDF]

Int J Mol Sci
Marileo AM, Lara CO, Sazo A, Contreras OV, González G, Castro PA, Aguayo LG, Moraga-Cid G, Fuentealba J, Burgos CF, Yévenes GE.   +10 more
europepmc   +1 more source