Results 111 to 120 of about 1,086 (210)
Journal of Microscopy, EarlyView.Abstract Deep Visual Proteomics (DVP) combines high‐resolution microscopy, computational instance segmentation, laser capture microdissection (LMD), and ultrasensitive mass spectrometry to enable spatially resolved molecular analysis of defined cellular populations.
Devon Siemes +10 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao +7 more
wiley +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang +6 more
wiley +1 more source
Biomedical Chromatography, Volume 40, Issue 8, August 2026.ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris +2 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 8, August 2026.Fermentation significantly altered the dominant bacterial genera from Sphingomonas and Pleomorphomonas (before fermentation) to Weissella and Lactobacillus (after fermentation), while Cladosporium and Fusarium remained the dominant fungal genera. Notably, non‐volatile compounds in de‐pulping coffee beans and volatile compounds of roasted coffee beans ...
Xiaojing Shen +8 more
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 8, August 2026.This study evaluated the 3‐month safety and tolerability of the probiotic CP‐9 in healthy infants aged 6 to 36 months. The research confirmed that, under the conditions of this study, CP‐9 can safely enrich specific beneficial bacterium in the gut without any obvious short‐term safety signal. ABSTRACT Infancy represents a critical period for growth and
Liujing Zhang +15 more
wiley +1 more source
Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α‐Cells
Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7149-7160, August 2026.ABSTRACT Aims Insulin resistance and obesity‐associated inflammation are key drivers in the pathogenesis of Type 2 diabetes mellitus (T2DM). Whilst inflammatory cytokines are well known to impair β‐cell function, their impact on pancreatic α‐cells and glucagon (GCG) regulation remains poorly understood. In this study, we investigated the effects of the
Caroline Bickelmann +5 more
wiley +1 more source
Heterologous production of oligopeptides with antihypertensive effects in Lactuca sativa and Medicago truncatula [PDF]
, 2018 “In the current scenario of a worldwide problematic situation related to cardiovascular diseases associated with hypertension, the necessity for alternative therapies has become a great challenge.
Oliveira, Filipe Silva Nunes de
core
The pharmaceutics from the foreign empire: the molecular pharming of the prokaryotic staphylokinase in Arabidopsis thaliana plants. [PDF]
World J Microbiol Biotechnol, 2016 Hnatuszko-Konka K +6 more
europepmc +1 more source