Results 111 to 120 of about 6,281,447 (337)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Metastable Innershell Molecular State (MIMS)

open access: yes, 2008
We propose that the existence of Metastable Innershell Molecular State (MIMS) was experimentally discovered by Bae et al. in hypervelocity (v>100km/s) impact of nanoparticles. The decay of MIMS resulted in the observed intense soft x-rays in the range of
Ashley   +14 more
core   +1 more source

From Proteins to Perturbed Hamiltonians: A Suite of Tutorials for the GROMACS-2018 Molecular Simulation Package [Article v1.0]

open access: yesLiving journal of computational molecular science, 2019
This LiveCoMS document is maintained online on GitHub at https: //github.com/jalemkul/ gmx_tutorials_livecoms; to provide feedback, suggestions, or help improve it, please visit the GitHub repository and participate via the issue tracker.
Justin A. Lemkul
semanticscholar   +1 more source

Research Investigation Directed Toward Extending the Useful Range of the Electromagnetic Spectrum [PDF]

open access: yes
The report discusses completed and proposed research in atomic and molecular physics conducted at the Columbia Radiation Laboratory from July 1972 to June 1973.
Happer, W., Hartmann, S. R.
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Ab initio investigation of the melting line of nitrogen at high pressure

open access: yes, 2010
Understanding the behavior of molecular systems under pressure is a fundamental problem in condensed matter physics. In the case of nitrogen, the determination of the phase diagram and in particular of the melting line, are largely open problems.
Donadio, Davide   +4 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Molecular Spectra, Reaction Dynamics, Symmetries and Life

open access: yesCHIMIA, 2003
We provide a short review of the work of the group for molecular kinetics and spectroscopy at the Laboratory for Physical Chemistry of ETH Zürich contributing to our understanding of the fundamental physical-chemical primary processes in ...
Martin Quack
doaj   +1 more source

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