Results 41 to 50 of about 261,173 (297)

Applications of scanning probe microscopy in neuroscience research

open access: yesJPhys Materials
Scanning probe microscopy techniques allow for label-free high-resolution imaging of cells, tissues, and biomolecules in physiologically relevant conditions.
Danielle M McRae, Zoya Leonenko
doaj   +1 more source

Ultrafast infrared spectroscopy with single molecular ions

open access: yesNew Journal of Physics, 2019
We propose a method to investigate the vibrational dynamics of single polyatomic molecular ions confined in a Paul trap. Quantum logic techniques are employed to detect the recoil of single photon absorption events on the molecule via a co-trapped atomic
Philipp Schindler
doaj   +1 more source

Probing Chiral Nanoparticles and Surfaces by Infrared Spectroscopy

open access: yesCHIMIA, 2006
Chiral metal surfaces and nanoparticles have the potential to be used for the selective production, the resolution and the detection of enantiomers of a chiral compound, which renders them highly attractive in view of the tremendous consequences
Cyrille Gautier   +5 more
doaj   +1 more source

Electronic structures and optical characteristics of fluorescent pyrazinoquinoxaline assemblies and Au interfaces

open access: yesScientific Reports, 2021
Understanding the excitonic processes at the interfaces of fluorescent π-conjugated molecules and metal electrodes is important for both fundamental studies and emerging applications. Adsorption configurations of molecules on metal surfaces significantly
Soyeong Kwon   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Challenges in “probing spectroscopic probes” for noninvasive simultaneous disease diagnosis

open access: yesFrontiers in Chemistry
Noninvasive diagnosis of human diseases relies on the detection of molecular markers (probes) in a painless manner. Although extrinsic and intrinsic molecular markers are often used, intrinsic disease probes (molecular markers) are preferable because ...
Lopamudra Roy   +12 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Label-free phenotypic profiling identified D-luciferin as a GPR35 agonist. [PDF]

open access: yesPLoS ONE, 2012
Fluorescent and luminescent probes are essential to both in vitro molecular assays and in vivo imaging techniques, and have been extensively used to measure biological function.
Haibei Hu, Huayun Deng, Ye Fang
doaj   +1 more source

Synthesis and Bioconjugation of Gold Nanoparticles as Potential Molecular Probes for Light‐Based Imaging Techniques [PDF]

open access: yesInternational Journal of Biomedical Imaging, 2007
We have synthesized and characterized gold nanoparticles (spheres and rods) with optical extinction bands within the “optical imaging window.” The intense plasmon resonant driven absorption and scattering peaks of these nanoparticles make them suitable as contrast agents for optical imaging techniques.
Rayavarapu, Raja Gopal   +5 more
openaire   +6 more sources

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