Results 41 to 50 of about 272,652 (264)
Ultrafast infrared spectroscopy with single molecular ions
New Journal of Physics, 2019 We propose a method to investigate the vibrational dynamics of single polyatomic molecular ions confined in a Paul trap. Quantum logic techniques are employed to detect the recoil of single photon absorption events on the molecule via a co-trapped atomic
Philipp Schindler
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Probing Chiral Nanoparticles and Surfaces by Infrared Spectroscopy
CHIMIA, 2006 Chiral metal surfaces and nanoparticles have the potential to be used for the selective production, the resolution and the detection of enantiomers of a chiral compound, which renders them highly attractive in view of the tremendous consequences
Cyrille Gautier +5 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Scientific Reports, 2021 Understanding the excitonic processes at the interfaces of fluorescent π-conjugated molecules and metal electrodes is important for both fundamental studies and emerging applications. Adsorption configurations of molecules on metal surfaces significantly
Soyeong Kwon +8 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Label-Free Target Discovery Strategy for Natural Active Products
BiomoleculesThe growing interest in harnessing natural compounds for health and medical applications underscores the necessity for innovative approaches to decipher their mechanisms of action.
Lei Shan +4 more
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Sum-Frequency Vibrational Spectroscopy on Chiral Liquids: A Novel Technique to Probe Molecular Chirality [PDF]
Physical Review Letters, 2000 Optical activity in sum-frequency vibrational spectra has been observed for the first time in chiral liquids. The electric-dipole allowed chiral element of the nonlinear susceptibility appears to be 3 orders of magnitude smaller than typical allowed achiral elements.
M A, Belkin +4 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Molecular contrast in optical coherence tomography using a pump-probe technique and a optical switch suppression technique [PDF]
SPIE Proceedings, 2003 We describe two novel technique for contrast enhancement in optical coherence tomography (OCT) which enables molecular specific imaging. The first, a pump-probe technique, is employed in which a pulsed pump laser is tuned to ground-state absorption in a molecule of interest.
Yang, Changhuei +5 more
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