Results 101 to 110 of about 631,116 (314)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fluorescence and fluorescent life imaging probes for biomedical applications
In my talk I will describe the development of a suite of fluorescent probes for the specific imaging of disease. This ranges from molecules that have been applied in vivo for the detection of cancer or fibrosis and bacterial lung infections, to probes ...
Bradley, M +1 more
core +1 more source
Frontiers in ImmunologyBackgroundObesity is a metabolic and chronic inflammatory disease involving genetic and environmental factors. This study aimed to investigate the causal relationship among gut microbiota abundance, plasma metabolomics, peripheral cell (blood and immune ...
Ying Li +17 more
doaj +1 more source
Nanomaterials, 2019 A label-free electrochemical aptasensor was fabricated to sensitively determine malachite green (MG) based on Au nanoparticles/graphene quantum dots-tungsten disulfide nanosheet composite film modified glassy carbon electrode (AuNPs/GQDs-WS2/GCE).
Qianqian Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Multicolor chromosome bar codes [PDF]
, 2006 Chromosome bar codes are multicolor banding patterns produced by fluorescence in situ hybridization (FISH) with differentially labeled and pooled sub-regional DNA probes.
Müller, Stefan, Wienberg, Johannes
core +1 more source
International Journal of Electrochemical Science, 2017 A silver hexacyanoferrate-graphene hybrid modified glassy carbon electrode is put forward in sensing of uric acid (UA) and dopamine (DA) in this work.
Fenghua Zhang +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Nature CommunicationsMyocardial ischemia (MI), caused by insufficient blood supply, is a pathological condition where cardiomyocytes lack oxygen and energy supply. Herein, we developed a natural photosynthetic system (HCU) consisting of chlorella pyrenoidosa (C.
Yuan Cheng +7 more
doaj +1 more source
International Journal of Electrochemical Science, 2017 The determination of cancer biomarkers plays an important role in early cancer screening and disease diagnosis. Herein, we designed a sandwiched “signal on” electrochemiluminescence (ECL) immunosensor to alpha fetoprotein (AFP) using gold nanoparticle ...
Jiangru Wang +5 more
doaj +1 more source