Results 91 to 100 of about 1,377,862 (341)

Polycation-π Interactions Are a Driving Force for Molecular Recognition by an Intrinsically Disordered Oncoprotein Family [PDF]

, 2013
Molecular recognition by intrinsically disordered proteins (IDPs) commonly involves specific localized contacts and target-induced disorder to order transitions.
A Arvand, A Bertolotti, A Bhattacherjee, A Boro, A Zarrine-Afsar, AB Sigalov, AG Turjanski, AH Mao, AH Mao, AK Dunker, AS Mahadevi, AS Reddy, AS Reddy, AY Tan, BA Shoemaker, C Haynes, D Alex, D Vijay, ED Ross, F Jin, G Gill, GM Lee, Guanghong Wei, HJ Dyson, HS Ashbaugh, HS Chan, HS Chan, Hue Sun Chan, HV Erkizan, HV Erkizan, I Staneva, J Danielsson, J Kim, J Singh, J Wang, J Wang, JC Hansen, JC Ma, JF Rual, Jianhui Song, JMR Baker, JP Gallivan, JP Gallivan, JS Barber-Rotenberg, JS Rao, JW Caldwell, Kevin A. W. Lee, KP Ng, KP Ng, KP Ng, L Feng, LM Iakoucheva, LM Salonen, M Azuma, M Borg, M Fuxreiter, M Levitt, MA Pufall, MS Cortese, MS Marshall, P Nash, P Tompa, P Tompa, PB Crowley, Peter Tompa, PJ Grohar, Q Lu, R Bachmaier, R Janknecht, R Petermann, R Wu, S Abeln, Sheung Chun Ng, SK Burley, SM Butterfield, T Mittag, T Mittag, V Neduva, VJ Hilser, VN Uversky, W Wang, W Zhong, X Chu, X Chu, X Xiu, Y Huang, Y Huang, Y Huang, Z Zhang   +88 more
core   +3 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Vicia incisa (Fabaceae). Taxonomical and chorological notes [PDF]

, 2017
The classification of the Vicia sativa aggregate is unsatisfactory. Concerning the taxonomic value and choice of rank of some of these taxa, there are disagreements among botanists.
Abbate, G., Iamonico, D., Iberite, M.
core   +1 more source

Getting to grips with ammonium

eLife, 2013
A fluorescent sensor that can monitor levels of extracellular ammonium has been made by using a fused green fluorescent protein to detect conformational changes in ammonium transport proteins.
Yi Wang, Jonathan A Javitch
doaj   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Decoding Pure Rotational Molecular Spectra for Asymmetric Molecules [PDF]

, 2012
In this paper we demonstrate how asymmetric molecular rotational spectra may be introduced to students both "pictorially" and with simple formulae. It is shown that the interpretation of such spectra relies heavily upon pattern recognition.
Cooke, S. A., Ohring, P.
core   +3 more sources

Allosteric Antagonism of the A_2A Adenosine Receptor by a Series of Bitopic Ligands

Cells, 2020
Allosteric antagonism by bitopic ligands, as reported for many receptors, is a distinct modulatory mechanism. Although several bitopic A2A adenosine receptor (A2AAR) ligand classes were reported as pharmacological tools, their receptor binding and ...
Zhan-Guo Gao, Kiran S. Toti, Ryan Campbell, R. Rama Suresh, Huijun Yang, Kenneth A. Jacobson   +5 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Molecular recognition by van der Waals interaction between polymers with sequence-specific polarizabilities

, 2015
We analyze van der Waals interactions between two rigid polymers with sequence-specific, anisotropic polarizabilities along the polymer backbones, so that the dipole moments fluctuate parallel to the polymer backbones.
Lu, Bing-Sui, Naji, Ali, Podgornik, Rudolf   +2 more
core   +1 more source