Results 71 to 80 of about 5,633,983 (314)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Stereoselective rhodium-catalyzed reaction of allenes with organoboronic reagents for diversified branched 1,3-alkadienes

Nature Communications
The terminal isoprene unit, as the simplest branched 1,3-diene unit, exists in a wide range of natural products and bioactive molecules. Herein, we report a stereoselective rhodium-catalyzed reaction of allenes with readily available methyl pinacol ...
Weiyi Wang, Shichao Hong, Wenxiang He, Xue Zhang, Hui Qian, Shengming Ma   +5 more
doaj   +1 more source

Natural Fish Trap‐Like Nanocage for Label‐Free Capture of Circulating Tumor Cells

Advanced Science, 2020
Nanomaterials have achieved several breakthroughs in the capture of circulating tumor cells (CTCs) over the past decades. However, artificial fabrication of label‐free nanomaterials used for high‐efficiency CTC capture is still a challenge.
Wenning Jiang, Lulu Han, Liwei Yang, Ting Xu, Jiabei He, Ruilian Peng, Ziyu Liu, Chong Zhang, Xiaomin Yu, Lingyun Jia   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Circularly polarized luminescence with high dissymmetry factors for achiral organic molecules in solutions

Nature Communications
Circularly polarized luminescence (CPL) in solution offers several advantages. However, it remains challenging for organic molecules to achieve circularly polarized luminescence with high dissymmetry factor (g lum) in solution. Herein, a general strategy
Ming-Jun Ji, Wen-Long Zhao, Meng Li, Chuan-Feng Chen   +3 more
doaj   +1 more source

A Synthetic Mimic of Inhibitor Binding in Phosphodiesterase Type 5 based on Corona Phase Molecular Recognition of Single Walled Carbon Nanotubes [PDF]

, 2018
Molecular recognition binding sites that specifically identify a target molecule are essential for research in the life sciences, clinical diagnoses and therapeutic development.
Imon, Rahaman, Juyao, Dong, Jessica, Sun, Ananth, Rajan, Michael, Strano, Michael, Lee, Daniel, Salem   +6 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Ultrasensitive Fluorescence Sensing of Chlorpyrifos Using Core–Shell Au@Ag Nanoparticle-Enhanced Inner Filter Effect on g-C₃N₄

Biosensors
In this work, we developed a novel, ultrasensitive fluorescence sensing platform for determination of organophosphorus pesticides (OPs), using chlorpyrifos as a representative model analyte.
Mengli Wang, Yuanyuan Xia, Yulei Li, Lifen Chen, Kunyan Wang, Shuangshuang Wu, Yuelan Zhang   +6 more
doaj   +1 more source

Complexation of 2,6-helic[6]arene and its derivatives with 1,1′-dimethyl-4,4′-bipyridinium salts and protonated 4,4'-bipyridinium salts: an acid–base controllable complexation

Beilstein Journal of Organic Chemistry, 2019
2,6-Helic[6]arene and its derivatives were synthesized, and their complexation with 1,1′-dimethyl-4,4′-bipyridinium and protonated 4,4'-bipyridinium salts were investigated in detail. It was found that the helic[6]arene and its derivatives could all form
Jing Li, Qiang Shi, Ying Han, Chuan-Feng Chen   +3 more
doaj   +1 more source

Advances and Challenges in Protein-Ligand Docking

, 2010
Molecular docking is a widely-used computational tool for the study of molecular recognition, which aims to predict the binding mode and binding affinity of a complex formed by two or more constituent molecules with known structures. An important type of
Sheng-You Huang, Xiaoqin Zou
core   +1 more source