Results 91 to 100 of about 5,633,983 (314)
Cooperative Control of Ion and Molecular Recognition by Molecular Assembling
, 2016 Cooperative Control of Ion and Molecular Recognition by Molecular ...
Takeshi Hanami (186392) +5 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
'Identify' and 'lock in': molecular integration during synaptic target recognition
, 1999 Synaptic target recognition is a complex molecular event. In a differentiating presynaptic terminal, relatively 'rare' molecules first detect the cell identity of the synaptic target.
Hoang, B, Chiba, A
core +1 more source
metalloendopeptidase using molecular docking analysis
, 2022 Jatropha mollissima is endemic to Brazil and is used for traditional medicinal purposes, including the treatment of snakebite. In this study, latex obtained from this plant was fractioned using reversed-phase chromatography, and the fractions were then ...
Stephen P. Mackessy +11 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Beilstein Journal of Organic ChemistryThe efficient binding of dicarboxylates represents an important yet challenging issue in supramolecular chemistry. In this study, we designed functional ultracycles as hosts to accommodate large organic dicarboxylate anions.
Wen-Hui Mi +5 more
doaj +1 more source
Getting to grips with ammonium
eLife, 2013 A fluorescent sensor that can monitor levels of extracellular ammonium has been made by using a fused green fluorescent protein to detect conformational changes in ammonium transport proteins.
Yi Wang, Jonathan A Javitch
doaj +1 more source
Molecular recognition applied to sensors [PDF]
, 1995 The role of molecular recognition by synthetic receptor molecules in the signal generation of CHEMFET sensors is discussed together with their self-organization on gold ...
Reinhoudt, David
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source