Results 51 to 60 of about 813,980 (316)
Intrinsically Disordered Proteins in Bcl-2 Regulated Apoptosis
, 2010 Intrinsic cell death is mediated by interaction between pro-apoptotic and pro-survival proteins of the B-cell lymphoma-2 (Bcl-2) family. Members of this family are either intrinsically disordered or contain intrinsically disordered regions/domains that ...
Rautureau, Hinds, Day
core +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
, 2011 Anchor residues, which are deeply buried upon binding, play an important role in protein-protein interactions by providing recognition specificity and facilitating the binding kinetics.
Zhirong Liu +3 more
core +1 more source
Non-C 2 symmetric chiral ligand dictating allyl-allyl coupling
Nature CommunicationsEnantioselective synthesis of chiral compounds is of high interest due to their importance in organic chemistry, medicinal chemistry, life science, and materials science.
Zhengshuai Xu, Hui Qian, Shengming Ma
doaj +1 more source
Enantioselective Diels–Alder reaction of anthracene by chiral tritylium catalysis
Beilstein Journal of Organic Chemistry, 2019 The combination of the trityl cation and a chiral weakly coordinating Fe(III)-based bisphosphate anion was used to develop a new type of a highly active carbocation Lewis acid catalyst.
Qichao Zhang, Jian Lv, Sanzhong Luo
doaj +1 more source
Research, 2022 Evaluating tumor development is of great importance for clinic treatment and therapy. It has been known that the amounts of sialic acids on tumor cell membrane surface are closely associated with the degree of cancerization of the cell. So, in this work,
Liangfen Cheng +7 more
doaj +1 more source
Chemical Engineering Journal Advances, 2021 Fabrication of novel magnetic porous materials for efficient magnetic adsorption and removal of environmental contaminants still remains great important and interesting in environmental science.
Xin-Qiao He +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Molecular recognition of the catalytic zinc(II) ion in MMP-13 : structure-based evolution of an allosteric inhibitor to dual binding mode inhibitors with improved lipophilic ligand efficiencies [PDF]
, 2016 Matrix metalloproteinases (MMPs) are a class of zinc dependent endopeptidases which play a crucial role in a multitude of severe diseases such as cancer and osteoarthritis.
Riedl, Rainer +3 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai +4 more
wiley +1 more source