Results 101 to 110 of about 1,377,862 (341)

Induced folding in RNA recognition by Arabidopsis thaliana DCL1 [PDF]

, 2015
DCL1 is the ribonuclease that carries out miRNA biogenesis in plants. The enzyme has two tandem double stranded RNA binding domains (dsRBDs) in its C-terminus.
Benoit Matthieu P. M. H., Boisbouvier, Jerome, Burdisso, Paula, Rasia, Rodolfo Maximiliano, Suarez, Irina Paula   +4 more
core   +1 more source

Radically enhanced molecular recognition

Nature Chemistry, 2009
The tendency for viologen radical cations to dimerize has been harnessed to establish a recognition motif based on their ability to form extremely strong inclusion complexes with cyclobis(paraquat-p-phenylene) in its diradical dicationic redox state.
William A. Goddard, Ali Trabolsi, Ali Trabolsi, Ekaterina Tkatchouk, Matthew E. Belowich, Diego Benitez, Michael R. Wasielewski, Douglas C. Friedman, Albert C. Fahrenbach, Karla K. Cotí, Karla K. Cotí, Raanan Carmielli, Michael T. Colvin, J. Fraser Stoddart, Niveen M. Khashab, Niveen M. Khashab, John Carl Olsen, John Carl Olsen, Hussam A. Khatib, Hussam A. Khatib   +19 more
openaire   +5 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Fluorescence and phosphorescence from individual C$_{60}$ molecules excited by local electron tunneling

, 2005
Using the highly localized current of electrons tunneling through a double barrier Scanning Tunneling Microscope (STM) junction, we excite luminescence from a selected C$_{60}$ molecule in the surface layer of fullerene nanocrystals grown on an ultrathin
Blüm, Marie-Christine, Chergui, Majed, Patthey, François, Pivetta, Marina, Schneider, Wolf-Dieter, Ćavar, Elizabeta   +5 more
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Radically enhanced molecular recognition [PDF]

, 2010
The tendency for viologen radical cations to dimerize has been harnessed to establish a recognition motif based on their ability to form extremely strong inclusion complexes with cyclobis(paraquat-p-phenylene) in its diradical dicationic redox state ...
Belowich, Matthew E., Benítez, Diego, Carmielli, Raanan, Colvin, Michael T., Cotí, Karla K., Fahrenbach, Albert C., Friedman, Douglas C., Goddard, William A., III, Khashab, Niveen, Khatib, Hussam A., Olsen, John-Carl, Stoddart, J. Fraser, Tkatchouk, Ekaterina, Trabolsi, Ali, Wasielewski, Michael R.   +14 more
core  

Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA [PDF]

, 2011
A furan amino acid, inspired by the recently discovered proximicin natural products, was incorporated into the scaffold of a DNA-binding hairpin polyamide.
Arcamone F., Belitsky J. M., Best T. P., Boger D. L., Bremer R. E., Chenoweth D. M., Daniel A. Gubler, Dervan P. B., Dervan P. B., Doss R. M., Edelson B. S., Fiedler H. P., Jevgenij A. Raskatov, Jordan L. Meier, Katy A. Muzikar, Kopka M. L., Marques M. A., Matsuda H., Mrksich M., Muzikar K. A., Nickols N. G., Nickols N. G., Olenyuk B. Z., Pelton J. G., Peter B. Dervan, Pilch D. S., Renneberg D., Schneider K., Stover J. S., Wade W. S., White S., Wolter F. E., Woods C. R.   +32 more
core   +3 more sources

Dicarboxylate recognition based on ultracycle hosts through cooperative hydrogen bonding and anion–π interactions

Beilstein Journal of Organic Chemistry
The efficient binding of dicarboxylates represents an important yet challenging issue in supramolecular chemistry. In this study, we designed functional ultracycles as hosts to accommodate large organic dicarboxylate anions.
Wen-Hui Mi, Teng-Yu Huang, Xu-Dong Wang, Yu-Fei Ao, Qi-Qiang Wang, De-Xian Wang   +5 more
doaj   +1 more source

Generation and Application of Fluorescent Anti-Human β2-Microglobulin VHHs via Amino Modification

Molecules, 2019
The functionalization of VHHs enables their application in almost every aspect of biomedical inquiry. Amino modification remains a common strategy for protein functionalization, though is considered to be inferior to site-specific methods and cause ...
Chundong Huang, Da Li, Jun Ren, Fangling Ji, Lingyun Jia   +4 more
doaj   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source