Results 101 to 110 of about 6,845,981 (383)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Getting to grips with ammonium

eLife, 2013
A fluorescent sensor that can monitor levels of extracellular ammonium has been made by using a fused green fluorescent protein to detect conformational changes in ammonium transport proteins.
Yi Wang, Jonathan A Javitch
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Molecular recognition by van der Waals interaction between polymers with sequence-specific polarizabilities

, 2015
We analyze van der Waals interactions between two rigid polymers with sequence-specific, anisotropic polarizabilities along the polymer backbones, so that the dipole moments fluctuate parallel to the polymer backbones.
Lu, Bing-Sui, Naji, Ali, Podgornik, Rudolf   +2 more
core   +1 more source

Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA [PDF]

, 2011
A furan amino acid, inspired by the recently discovered proximicin natural products, was incorporated into the scaffold of a DNA-binding hairpin polyamide.
Arcamone F., Belitsky J. M., Best T. P., Boger D. L., Bremer R. E., Chenoweth D. M., Daniel A. Gubler, Dervan P. B., Dervan P. B., Doss R. M., Edelson B. S., Fiedler H. P., Jevgenij A. Raskatov, Jordan L. Meier, Katy A. Muzikar, Kopka M. L., Marques M. A., Matsuda H., Mrksich M., Muzikar K. A., Nickols N. G., Nickols N. G., Olenyuk B. Z., Pelton J. G., Peter B. Dervan, Pilch D. S., Renneberg D., Schneider K., Stover J. S., Wade W. S., White S., Wolter F. E., Woods C. R.   +32 more
core   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Radically enhanced molecular recognition [PDF]

, 2010
The tendency for viologen radical cations to dimerize has been harnessed to establish a recognition motif based on their ability to form extremely strong inclusion complexes with cyclobis(paraquat-p-phenylene) in its diradical dicationic redox state ...
Belowich, Matthew E., Benítez, Diego, Carmielli, Raanan, Colvin, Michael T., Cotí, Karla K., Fahrenbach, Albert C., Friedman, Douglas C., Goddard, William A., III, Khashab, Niveen, Khatib, Hussam A., Olsen, John-Carl, Stoddart, J. Fraser, Tkatchouk, Ekaterina, Trabolsi, Ali, Wasielewski, Michael R.   +14 more
core  

The physical language of molecular codes: A rate-distortion approach to the evolution and emergence of biological codes

, 2010
The function of the organism hinges on the performance of its information-processing networks, which convey information via molecular recognition. Many paths within these networks utilize molecular codebooks, such as the genetic code, to translate ...
Tlusty, Tsvi
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Polymer adsorption onto random planar surfaces: Interplay of polymer and surface correlation

, 2005
We study the adsorption of homogeneous or heterogeneous polymers onto heterogeneous planar surfaces with exponentially decaying site-site correlations, using a variational reference system approach.
Alexey Polotsky, Andreas Degenhard, Friederike Schmid, Joanny J.-F.   +3 more
core   +1 more source