Results 121 to 130 of about 31,759,038 (276)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Selection of extra virgin olive oils for an international award : sensory analysis and spectroscopic control

, 2009
The Panel of the Department of Food Science (University of Bologna), recognized by the Italian Ministry in 2006, was involved in the sensory analysis of 112 extra virgin olive oils (coming both from Italy and from others countries) with the aim, in the ...
A. Bendini, CERRETANI, LORENZO, V. Di Egidio, L. Cerretani, BENDINI, ALESSANDRA, N. Sinelli, E. Casiraghi   +6 more
core  

Identification of Key Aroma-Active Compounds in Plum, Jujube, and Grape Extracts via GC×GC-O-TOF-MS, GC-MS, Aroma Recombination and Omission Tests

Separations
Fruity natural flavors are widely used in food, cosmetics, and tobacco products, and their flavor profiles directly affect the sensory quality of the final products.
Ruiyang Chen, Qinghui Jia, Anzhen Fu, Fan Yang, Yixin Dai, Jingzhe Sun, Liya Liu, Ye Liu, Shuang Bi   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sensory characteristics of meat from steers of various breeds and rearing intensities [Elektronisk resurs]

, 2019
The most common category of young cattle slaughtered for beef in Sweden is bulls of dairy breed, most often reared indoors. There is however a potential in raising steers (castrated bulls) for slaughter on semi-natural pasture, which may have an impact ...
Karlsson, Anders H.,, Stenberg, Elin,, Kristianstad University., Olsson, Viktoria,, Arvidsson-Segerkvist, Katarina,, Hessle, Anna,, Wendin, Karin,   +6 more
core  

International Journal of Molecular Science [PDF]

Neurological symptoms associated with COVID-19, acute and long term, suggest SARS-CoV-2 affects both the peripheral and central nervous systems (PNS/CNS).
Tina M. Taylor, Hawks, Seth A., Bertke, Andrea S., Poorna Goswami, Emma Leslie, Matthew D. Irwin, Jillian C. Green, Andrea S. Bertke, Mo Jia, Thompson, Christopher K., Greyson A. Moore, Leslie, Emma, Duggal, Nisha K., Taylor, Tina M., Harrell, Telvin L., Nisha K. Duggal, Seth A. Hawks, Christopher K. Thompson, Jonathan D. Joyce, Irwin, Matthew D., Telvin L. Harrell, Moore, Greyson A., Goswami, Poorna, Green, Jillian C., Joyce, Jonathan D., Jia, Mo   +25 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Characterization and comparison of key aroma compounds in traditional and rapid Yongchuan douchi by molecular sensory science

LWT, 2023
yuying Liu, Wei Li, Qian Tan, zhihua Li, Hongwei Wang, Huayi Suo   +5 more
openaire   +1 more source