Results 191 to 200 of about 254,467 (221)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

CRESSENT: a bioinformatics toolkit to explore and improve ssDNA virus annotation. [PDF]

Microb Genom
Pavan RR, Sullivan MB, Tisza MJ.
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The reference genome sequence of the scarlet follicle, Sterculia lanceolata, reveals a paleo-polyploidization and its impact on fruit quality and fruit dehiscence. [PDF]

Funct Integr Genomics
Hu Y, Zhang Y, Zhang H, Zhang J, Guo G, Yang K, Shao BY, Xue JY, Henry R, Wang W, Chen F.   +10 more
europepmc   +1 more source

Whole-genome sequencing of <i>Escherichia coli</i> DH5α using MinION nanopore technology. [PDF]

Microbiol Resour Announc
Kumar MS, Suneesh P, Bhat Krishna M, Soman K, Satheesh Babu T.   +4 more
europepmc   +1 more source

De Novo Genome Assembly, Genomic Features, and Comparative Analysis of the Sawfly <i>Dentathalia scutellariae</i>. [PDF]

Biology (Basel)
Wang S, Liu C, Mei Y, Yang D, Pang H, Wang F, Ye G, Fang Q, Ye X, Yang Y.   +9 more
europepmc   +1 more source

Divergent Amplification of Y-Linked Dosage-Sensitive Genes Triggers Regulatory Mismatch Underlying Cattle-Yak Male Sterility. [PDF]

Biomolecules
Wang Y, Chen Y, Zhu Z, Zeng X, Ha W, Su L, Hu L, Liu Y, Li B, Loor J, Jiang M.   +10 more
europepmc   +1 more source

A chromosome-scale assembly and comparative genomics of the Yunnanopilia longistaminata. [PDF]

Sci Data
Zhou Y, Liu G, Wang L, Liu J, Liu Z, Li S, Wang D.   +6 more
europepmc   +1 more source